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14 results

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Page 1
Design and synthesis of potent, orally bioavailable dihydroquinazolinone inhibitors of p38 MAP kinase.
Stelmach JE, Liu L, Patel SB, Pivnichny JV, Scapin G, Singh S, Hop CE, Wang Z, Strauss JR, Cameron PM, Nichols EA, O'Keefe SJ, O'Neill EA, Schmatz DM, Schwartz CD, Thompson CM, Zaller DM, Doherty JB. Stelmach JE, et al. Among authors: schwartz cd. Bioorg Med Chem Lett. 2003 Jan 20;13(2):277-80. doi: 10.1016/s0960-894x(02)00752-7. Bioorg Med Chem Lett. 2003. PMID: 12482439
Hybrid-designed inhibitors of p38 MAP kinase utilizing N-arylpyridazinones.
Colletti SL, Frie JL, Dixon EC, Singh SB, Choi BK, Scapin G, Fitzgerald CE, Kumar S, Nichols EA, O'Keefe SJ, O'Neill EA, Porter G, Samuel K, Schmatz DM, Schwartz CD, Shoop WL, Thompson CM, Thompson JE, Wang R, Woods A, Zaller DM, Doherty JB. Colletti SL, et al. Among authors: schwartz cd. J Med Chem. 2003 Jan 30;46(3):349-52. doi: 10.1021/jm025585h. J Med Chem. 2003. PMID: 12540232
Pyridazine based inhibitors of p38 MAPK.
McIntyre CJ, Ponticello GS, Liverton NJ, O'Keefe SJ, O'Neill EA, Pang M, Schwartz CD, Claremon DA. McIntyre CJ, et al. Among authors: schwartz cd. Bioorg Med Chem Lett. 2002 Feb 25;12(4):689-92. doi: 10.1016/s0960-894x(01)00834-4. Bioorg Med Chem Lett. 2002. PMID: 11844702
p38MAP kinase inhibitors. Part 1: design and development of a new class of potent and highly selective inhibitors based on 3,4-dihydropyrido[3,2-d]pyrimidone scaffold.
Natarajan SR, Wisnoski DD, Singh SB, Stelmach JE, O'Neill EA, Schwartz CD, Thompson CM, Fitzgerald CE, O'Keefe SJ, Kumar S, Hop CE, Zaller DM, Schmatz DM, Doherty JB. Natarajan SR, et al. Among authors: schwartz cd. Bioorg Med Chem Lett. 2003 Jan 20;13(2):273-6. doi: 10.1016/s0960-894x(02)00876-4. Bioorg Med Chem Lett. 2003. PMID: 12482438
SAR of 3,4-dihydropyrido[3,2-d]pyrimidone p38 inhibitors.
Liu L, Stelmach JE, Natarajan SR, Chen MH, Singh SB, Schwartz CD, Fitzgerald CE, O'Keefe SJ, Zaller DM, Schmatz DM, Doherty JB. Liu L, et al. Among authors: schwartz cd. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3979-82. doi: 10.1016/j.bmcl.2003.08.059. Bioorg Med Chem Lett. 2003. PMID: 14592489
L-156,602, a C5a antagonist with a novel cyclic hexadepsipeptide structure from Streptomyces sp. MA6348. Fermentation, isolation and structure determination.
Hensens OD, Borris RP, Koupal LR, Caldwell CG, Currie SA, Haidri AA, Homnick CF, Honeycutt SS, Lindenmayer SM, Schwartz CD, et al. Hensens OD, et al. Among authors: schwartz cd. J Antibiot (Tokyo). 1991 Feb;44(2):249-54. doi: 10.7164/antibiotics.44.249. J Antibiot (Tokyo). 1991. PMID: 2010362 Free article. No abstract available.
Novel and potent gastrin and brain cholecystokinin antagonists from Streptomyces olivaceus. Taxonomy, fermentation, isolation, chemical conversions, and physico-chemical and biochemical properties.
Lam YK, Bogen D, Chang RS, Faust KA, Hensens OD, Zink DL, Schwartz CD, Zitano L, Garrity GM, Gagliardi MM, et al. Lam YK, et al. Among authors: schwartz cd. J Antibiot (Tokyo). 1991 Jun;44(6):613-25. doi: 10.7164/antibiotics.44.613. J Antibiot (Tokyo). 1991. PMID: 1906451 Free article.
14 results