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Does the overexpression of pro-insulin-like growth factor-II in transfected human embryonic kidney fibroblasts increase the secretion of lysosomal enzymes?
Hoeflich A, Wolf E, Braulke T, Koepf G, Kessler U, Brem G, Rascher W, Blum W, Kiess W. Hoeflich A, et al. Among authors: kiess w. Eur J Biochem. 1995 Aug 15;232(1):172-8. doi: 10.1111/j.1432-1033.1995.tb20796.x. Eur J Biochem. 1995. PMID: 7556147 Free article.
The two classes of ligands reciprocally modulate the binding of the other class of ligand to the receptor [Kiess, W., Thomas, C. L., Greenstein, L., Lee, L., Sklar, M. M., Rechler, M. M., Sahagian, G. ...
The two classes of ligands reciprocally modulate the binding of the other class of ligand to the receptor [Kiess, W., Thomas, …
Human osteosarcoma (U-2 OS) cells express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptors and synthesize IGF-II: autocrine growth stimulation by IGF-II via the IGF-I receptor.
Raile K, Höflich A, Kessler U, Yang Y, Pfuender M, Blum WF, Kolb H, Schwarz HP, Kiess W. Raile K, et al. Among authors: kiess w. J Cell Physiol. 1994 Jun;159(3):531-41. doi: 10.1002/jcp.1041590317. J Cell Physiol. 1994. PMID: 8188767
880 results