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Multiple site place-of-care manufactured anti-CD19 CAR-T cells induce high remission rates in B-cell malignancy patients.
Maschan M, Caimi PF, Reese-Koc J, Sanchez GP, Sharma AA, Molostova O, Shelikhova L, Pershin D, Stepanov A, Muzalevskii Y, Suzart VG, Otegbeye F, Wald D, Xiong Y, Wu D, Knight A, Oparaocha I, Ferencz B, Roy A, Worden A, Kruger W, Kadan M, Schneider D, Orentas R, Sekaly RP, de Lima M, Dropulić B. Maschan M, et al. Nat Commun. 2021 Dec 10;12(1):7200. doi: 10.1038/s41467-021-27312-6. Nat Commun. 2021. PMID: 34893603 Free PMC article.
Real-time detection of enzymatically formed hydrogen sulfide by pathogenic variants of cystathionine beta-synthase using hemoglobin I of Lucina pectinata as a biosensor.
Myszkowska J, Klotz K, Leandro P, Kruger WD, Froese DS, Baumgartner MR, Spiekerkoetter U, Hannibal L. Myszkowska J, et al. Among authors: kruger wd. Free Radic Biol Med. 2024 Oct;223:281-295. doi: 10.1016/j.freeradbiomed.2024.07.031. Epub 2024 Jul 25. Free Radic Biol Med. 2024. PMID: 39067625 Free article.
Deciphering pathophysiological mechanisms underlying cystathionine beta-synthase-deficient homocystinuria using targeted metabolomics, liver proteomics, sphingolipidomics and analysis of mitochondrial function.
Majtan T, Olsen T, Sokolova J, Krijt J, Křížková M, Ida T, Ditrói T, Hansikova H, Vit O, Petrak J, Kuchař L, Kruger WD, Nagy P, Akaike T, Kožich V. Majtan T, et al. Among authors: kruger wd. Redox Biol. 2024 Jul;73:103222. doi: 10.1016/j.redox.2024.103222. Epub 2024 Jun 4. Redox Biol. 2024. PMID: 38843767 Free PMC article.
An orally administered enzyme therapeutic for homocystinuria that suppresses homocysteine by metabolizing methionine in the gastrointestinal tract.
Skvorak K, Mitchell V, Teadt L, Franklin KA, Lee HO, Kruse N, Huitt-Roehl C, Hang J, Du F, Galanie S, Guan S, Aijaz H, Zhang N, Rajkovic G, Kruger WD, Ismaili MHA, Huisman G, McCluskie K, Silverman AP. Skvorak K, et al. Among authors: kruger wd. Mol Genet Metab. 2023 Aug;139(4):107653. doi: 10.1016/j.ymgme.2023.107653. Epub 2023 Jul 12. Mol Genet Metab. 2023. PMID: 37463544 Free article.
110 results