König G - Search Results

1

Synthesis and structure activity relationships of novel small molecule cathepsin D inhibitors.

Dumas J, Brittelli D, Chen J, Dixon B, Hatoum-Mokdad H, König G, Sibley R, Witowsky J, Wong S. Dumas J, et al. Among authors: konig g. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2531-6. doi: 10.1016/s0960-894x(99)00433-3. Bioorg Med Chem Lett. 1999. PMID: 10498202

2

Brunsvicamides A-C: sponge-related cyanobacterial peptides with Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory activity.

Müller D, Krick A, Kehraus S, Mehner C, Hart M, Küpper FC, Saxena K, Prinz H, Schwalbe H, Janning P, Waldmann H, König GM. Müller D, et al. J Med Chem. 2006 Aug 10;49(16):4871-8. doi: 10.1021/jm060327w. J Med Chem. 2006. PMID: 16884299

3

Processing of the pre-beta-amyloid protein by cathepsin D is enhanced by a familial Alzheimer's disease mutation.

Dreyer RN, Bausch KM, Fracasso P, Hammond LJ, Wunderlich D, Wirak DO, Davis G, Brini CM, Buckholz TM, König G, et al. Dreyer RN, et al. Among authors: konig g. Eur J Biochem. 1994 Sep 1;224(2):265-71. doi: 10.1111/j.1432-1033.1994.00265.x. Eur J Biochem. 1994. PMID: 7523115 Free article.

4

Bcl-xl-specific antibody labels activated microglia associated with Alzheimer's disease and other pathological states.

Drache B, Diehl GE, Beyreuther K, Perlmutter LS, König G. Drache B, et al. Among authors: konig g. J Neurosci Res. 1997 Jan 1;47(1):98-108. J Neurosci Res. 1997. PMID: 8981243

5

Deciphering Specificity Determinants for FR900359-Derived G_q α Inhibitors Based on Computational and Structure-Activity Studies.

Reher R, Kühl T, Annala S, Benkel T, Kaufmann D, Nubbemeyer B, Odhiambo JP, Heimer P, Bäuml CA, Kehraus S, Crüsemann M, Kostenis E, Tietze D, König GM, Imhof D. Reher R, et al. ChemMedChem. 2018 Aug 20;13(16):1634-1643. doi: 10.1002/cmdc.201800304. Epub 2018 Jul 3. ChemMedChem. 2018. PMID: 29873888

6

Inhibition of heme detoxification processes underlies the antimalarial activity of terpene isonitrile compounds from marine sponges.

Wright AD, Wang H, Gurrath M, König GM, Kocak G, Neumann G, Loria P, Foley M, Tilley L. Wright AD, et al. Among authors: konig gm. J Med Chem. 2001 Mar 15;44(6):873-85. doi: 10.1021/jm0010724. J Med Chem. 2001. PMID: 11300869

7

New iantherans from the marine sponge Ianthella quadrangulata: novel agonists of the P2Y(11) receptor.

Greve H, Meis S, Kassack MU, Kehraus S, Krick A, Wright AD, König GM. Greve H, et al. J Med Chem. 2007 Nov 15;50(23):5600-7. doi: 10.1021/jm070043r. Epub 2007 Oct 17. J Med Chem. 2007. PMID: 17941622

8

Polyketides from the marine-derived fungus Ascochyta salicorniae and their potential to inhibit protein phosphatases.

Seibert SF, Eguereva E, Krick A, Kehraus S, Voloshina E, Raabe G, Fleischhauer J, Leistner E, Wiese M, Prinz H, Alexandrov K, Janning P, Waldmann H, König GM. Seibert SF, et al. Among authors: konig gm. Org Biomol Chem. 2006 Jun 7;4(11):2233-40. doi: 10.1039/b601386d. Epub 2006 May 3. Org Biomol Chem. 2006. PMID: 16729132

9

Leucamide A: a new cytotoxic heptapeptide from the Australian sponge Leucetta microraphis.

Kehraus S, König GM, Wright AD, Woerheide G. Kehraus S, et al. Among authors: konig gm. J Org Chem. 2002 Jul 12;67(14):4989-92. doi: 10.1021/jo020058r. J Org Chem. 2002. PMID: 12098321

10

A new cytotoxic calyculinamide derivative, geometricin A, from the Australian sponge Luffariella geometrica.

Kehraus S, König GM, Wright AD. Kehraus S, et al. J Nat Prod. 2002 Jul;65(7):1056-8. doi: 10.1021/np010544u. J Nat Prod. 2002. PMID: 12141875

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