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Expression of a dominant negative SHP-2 in transgenic mice induces insulin resistance.
Maegawa H, Hasegawa M, Sugai S, Obata T, Ugi S, Morino K, Egawa K, Fujita T, Sakamoto T, Nishio Y, Kojima H, Haneda M, Yasuda H, Kikkawa R, Kashiwagi A. Maegawa H, et al. Among authors: kashiwagi a. J Biol Chem. 1999 Oct 15;274(42):30236-43. doi: 10.1074/jbc.274.42.30236. J Biol Chem. 1999. PMID: 10514516 Free article.
Thiazolidine derivatives ameliorate high glucose-induced insulin resistance via the normalization of protein-tyrosine phosphatase activities.
Maegawa H, Ide R, Hasegawa M, Ugi S, Egawa K, Iwanishi M, Kikkawa R, Shigeta Y, Kashiwagi A. Maegawa H, et al. Among authors: kashiwagi a. J Biol Chem. 1995 Mar 31;270(13):7724-30. doi: 10.1074/jbc.270.13.7724. J Biol Chem. 1995. PMID: 7535776 Free article.
Both protein kinase C activities and phorbol dibutyrate binding to intact cells were unchanged; however, cytosolic protein-tyrosine phosphatase (PTPase) activity increased within 1 h prior to the impairment of insulin receptor kinase in HG cells (Maegawa, H., Tachikawa-Ide, R., U …
Both protein kinase C activities and phorbol dibutyrate binding to intact cells were unchanged; however, cytosolic protein-tyrosine phosphat …
641 results