Spencer DM - Search Results

1

Improved artificial death switches based on caspases and FADD.

Fan L, Freeman KW, Khan T, Pham E, Spencer DM. Fan L, et al. Among authors: spencer dm. Hum Gene Ther. 1999 Sep 20;10(14):2273-85. doi: 10.1089/10430349950016924. Hum Gene Ther. 1999. PMID: 10515447

2

Synthetic activation of caspases: artificial death switches.

MacCorkle RA, Freeman KW, Spencer DM. MacCorkle RA, et al. Among authors: spencer dm. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3655-60. doi: 10.1073/pnas.95.7.3655. Proc Natl Acad Sci U S A. 1998. PMID: 9520421 Free PMC article.

3

A novel conditional Akt 'survival switch' reversibly protects cells from apoptosis.

Li B, Desai SA, MacCorkle-Chosnek RA, Fan L, Spencer DM. Li B, et al. Among authors: spencer dm. Gene Ther. 2002 Feb;9(4):233-44. doi: 10.1038/sj.gt.3301641. Gene Ther. 2002. PMID: 11896462

4

Adenovirus-mediated transfer of inducible caspases: a novel "death switch" gene therapeutic approach to prostate cancer.

Shariat SF, Desai S, Song W, Khan T, Zhao J, Nguyen C, Foster BA, Greenberg N, Spencer DM, Slawin KM. Shariat SF, et al. Among authors: spencer dm. Cancer Res. 2001 Mar 15;61(6):2562-71. Cancer Res. 2001. PMID: 11289132

5

Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland.

Welm BE, Freeman KW, Chen M, Contreras A, Spencer DM, Rosen JM. Welm BE, et al. Among authors: spencer dm. J Cell Biol. 2002 May 13;157(4):703-14. doi: 10.1083/jcb.200107119. Epub 2002 May 13. J Cell Biol. 2002. PMID: 12011115 Free PMC article.

6

Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation.

Freeman KW, Gangula RD, Welm BE, Ozen M, Foster BA, Rosen JM, Ittmann M, Greenberg NM, Spencer DM. Freeman KW, et al. Among authors: spencer dm. Cancer Res. 2003 Oct 1;63(19):6237-43. Cancer Res. 2003. PMID: 14559809

7

Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice.

Freeman KW, Welm BE, Gangula RD, Rosen JM, Ittmann M, Greenberg NM, Spencer DM. Freeman KW, et al. Among authors: spencer dm. Cancer Res. 2003 Dec 1;63(23):8256-63. Cancer Res. 2003. PMID: 14678983

8

Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition.

Acevedo VD, Gangula RD, Freeman KW, Li R, Zhang Y, Wang F, Ayala GE, Peterson LE, Ittmann M, Spencer DM. Acevedo VD, et al. Among authors: spencer dm. Cancer Cell. 2007 Dec;12(6):559-71. doi: 10.1016/j.ccr.2007.11.004. Cancer Cell. 2007. PMID: 18068632 Free article.

9

Robust prostate-specific expression for targeted gene therapy based on the human kallikrein 2 promoter.

Xie X, Zhao X, Liu Y, Young CY, Tindall DJ, Slawin KM, Spencer DM. Xie X, et al. Among authors: spencer dm. Hum Gene Ther. 2001 Mar 20;12(5):549-61. doi: 10.1089/104303401300042483. Hum Gene Ther. 2001. PMID: 11268287

10

An inducible system for the study of FGF signalling in early amphibian development.

Pownall ME, Welm BE, Freeman KW, Spencer DM, Rosen JM, Isaacs HV. Pownall ME, et al. Among authors: spencer dm. Dev Biol. 2003 Apr 1;256(1):89-99. doi: 10.1016/s0012-1606(02)00120-3. Dev Biol. 2003. PMID: 12654294 Free article.

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