Chandy KG - Search Results

1

Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin.

Pennington MW, Lanigan MD, Kalman K, Mahnir VM, Rauer H, McVaugh CT, Behm D, Donaldson D, Chandy KG, Kem WR, Norton RS. Pennington MW, et al. Among authors: chandy kg. Biochemistry. 1999 Nov 2;38(44):14549-58. doi: 10.1021/bi991282m. Biochemistry. 1999. PMID: 10545177

2

Characterization of the transcription unit of mouse Kv1.4, a voltage-gated potassium channel gene.

Wymore RS, Negulescu D, Kinoshita K, Kalman K, Aiyar J, Gutman GA, Chandy KG. Wymore RS, et al. Among authors: chandy kg. J Biol Chem. 1996 Jun 28;271(26):15629-34. doi: 10.1074/jbc.271.26.15629. J Biol Chem. 1996. PMID: 8663090 Free article.

3

Novel nonpeptide agents potently block the C-type inactivated conformation of Kv1.3 and suppress T cell activation.

Nguyen A, Kath JC, Hanson DC, Biggers MS, Canniff PC, Donovan CB, Mather RJ, Bruns MJ, Rauer H, Aiyar J, Lepple-Wienhues A, Gutman GA, Grissmer S, Cahalan MD, Chandy KG. Nguyen A, et al. Among authors: chandy kg. Mol Pharmacol. 1996 Dec;50(6):1672-9. Mol Pharmacol. 1996. PMID: 8967992

4

Regulation of mammalian Shaker-related K+ channels: evidence for non-conducting closed and non-conducting inactivated states.

Jäger H, Rauer H, Nguyen AN, Aiyar J, Chandy KG, Grissmer S. Jäger H, et al. Among authors: chandy kg. J Physiol. 1998 Jan 15;506 ( Pt 2)(Pt 2):291-301. doi: 10.1111/j.1469-7793.1998.291bw.x. J Physiol. 1998. PMID: 9490854 Free PMC article.

5

ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide.

Kalman K, Pennington MW, Lanigan MD, Nguyen A, Rauer H, Mahnir V, Paschetto K, Kem WR, Grissmer S, Gutman GA, Christian EP, Cahalan MD, Norton RS, Chandy KG. Kalman K, et al. Among authors: chandy kg. J Biol Chem. 1998 Dec 4;273(49):32697-707. doi: 10.1074/jbc.273.49.32697. J Biol Chem. 1998. PMID: 9830012 Free article.

6

Calmodulin mediates calcium-dependent activation of the intermediate conductance KCa channel, IKCa1.

Fanger CM, Ghanshani S, Logsdon NJ, Rauer H, Kalman K, Zhou J, Beckingham K, Chandy KG, Cahalan MD, Aiyar J. Fanger CM, et al. Among authors: chandy kg. J Biol Chem. 1999 Feb 26;274(9):5746-54. doi: 10.1074/jbc.274.9.5746. J Biol Chem. 1999. PMID: 10026195 Free article.

7

UK-78,282, a novel piperidine compound that potently blocks the Kv1.3 voltage-gated potassium channel and inhibits human T cell activation.

Hanson DC, Nguyen A, Mather RJ, Rauer H, Koch K, Burgess LE, Rizzi JP, Donovan CB, Bruns MJ, Canniff PC, Cunningham AC, Verdries KA, Mena E, Kath JC, Gutman GA, Cahalan MD, Grissmer S, Chandy KG. Hanson DC, et al. Among authors: chandy kg. Br J Pharmacol. 1999 Apr;126(8):1707-16. doi: 10.1038/sj.bjp.0702480. Br J Pharmacol. 1999. PMID: 10372812 Free PMC article.

8

Structural conservation of the pores of calcium-activated and voltage-gated potassium channels determined by a sea anemone toxin.

Rauer H, Pennington M, Cahalan M, Chandy KG. Rauer H, et al. Among authors: chandy kg. J Biol Chem. 1999 Jul 30;274(31):21885-92. doi: 10.1074/jbc.274.31.21885. J Biol Chem. 1999. PMID: 10419508 Free article.

9

Structure-guided transformation of charybdotoxin yields an analog that selectively targets Ca(2+)-activated over voltage-gated K(+) channels.

Rauer H, Lanigan MD, Pennington MW, Aiyar J, Ghanshani S, Cahalan MD, Norton RS, Chandy KG. Rauer H, et al. Among authors: chandy kg. J Biol Chem. 2000 Jan 14;275(2):1201-8. doi: 10.1074/jbc.275.2.1201. J Biol Chem. 2000. PMID: 10625664 Free article.

10

Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels.

Fanger CM, Rauer H, Neben AL, Miller MJ, Rauer H, Wulff H, Rosa JC, Ganellin CR, Chandy KG, Cahalan MD. Fanger CM, et al. Among authors: chandy kg. J Biol Chem. 2001 Apr 13;276(15):12249-56. doi: 10.1074/jbc.M011342200. Epub 2001 Jan 22. J Biol Chem. 2001. PMID: 11278890 Free article.

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