Mahnir VM - Search Results

1

Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin.

Pennington MW, Lanigan MD, Kalman K, Mahnir VM, Rauer H, McVaugh CT, Behm D, Donaldson D, Chandy KG, Kem WR, Norton RS. Pennington MW, et al. Among authors: mahnir vm. Biochemistry. 1999 Nov 2;38(44):14549-58. doi: 10.1021/bi991282m. Biochemistry. 1999. PMID: 10545177

2

Chemical synthesis and characterization of ShK toxin: a potent potassium channel inhibitor from a sea anemone.

Pennington MW, Byrnes ME, Zaydenberg I, Khaytin I, de Chastonay J, Krafte DS, Hill R, Mahnir VM, Volberg WA, Gorczyca W, et al. Pennington MW, et al. Among authors: mahnir vm. Int J Pept Protein Res. 1995 Nov;46(5):354-8. doi: 10.1111/j.1399-3011.1995.tb01068.x. Int J Pept Protein Res. 1995. PMID: 8567178

3

Identification of three separate binding sites on SHK toxin, a potent inhibitor of voltage-dependent potassium channels in human T-lymphocytes and rat brain.

Pennington MW, Mahnir VM, Krafte DS, Zaydenberg I, Byrnes ME, Khaytin I, Crowley K, Kem WR. Pennington MW, et al. Among authors: mahnir vm. Biochem Biophys Res Commun. 1996 Feb 27;219(3):696-701. doi: 10.1006/bbrc.1996.0297. Biochem Biophys Res Commun. 1996. PMID: 8645244

4

An essential binding surface for ShK toxin interaction with rat brain potassium channels.

Pennington MW, Mahnir VM, Khaytin I, Zaydenberg I, Byrnes ME, Kem WR. Pennington MW, et al. Among authors: mahnir vm. Biochemistry. 1996 Dec 24;35(51):16407-11. doi: 10.1021/bi962463g. Biochemistry. 1996. PMID: 8987971

5

ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide.

Kalman K, Pennington MW, Lanigan MD, Nguyen A, Rauer H, Mahnir V, Paschetto K, Kem WR, Grissmer S, Gutman GA, Christian EP, Cahalan MD, Norton RS, Chandy KG. Kalman K, et al. J Biol Chem. 1998 Dec 4;273(49):32697-707. doi: 10.1074/jbc.273.49.32697. J Biol Chem. 1998. PMID: 9830012 Free article.

6

Anabaseine is a potent agonist on muscle and neuronal alpha-bungarotoxin-sensitive nicotinic receptors.

Kem WR, Mahnir VM, Papke RL, Lingle CJ. Kem WR, et al. Among authors: mahnir vm. J Pharmacol Exp Ther. 1997 Dec;283(3):979-92. J Pharmacol Exp Ther. 1997. PMID: 9399967

7

Pharmacokinetics and urinary excretion of DMXBA (GTS-21), a compound enhancing cognition.

Mahnir V, Lin B, Prokai-Tatrai K, Kem WR. Mahnir V, et al. Biopharm Drug Dispos. 1998 Apr;19(3):147-51. doi: 10.1002/(sici)1099-081x(199804)19:3<147::aid-bdd77>3.0.co;2-9. Biopharm Drug Dispos. 1998. PMID: 9569996

8

Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice.

Stevens KE, Kem WR, Mahnir VM, Freedman R. Stevens KE, et al. Among authors: mahnir vm. Psychopharmacology (Berl). 1998 Apr;136(4):320-7. doi: 10.1007/s002130050573. Psychopharmacology (Berl). 1998. PMID: 9600576

9

Investigation of the Possible Pharmacologically Active Forms of the Nicotinic Acetylcholine Receptor Agonist Anabaseine.

Andrud K, Xing H, Gabrielsen B, Bloom L, Mahnir V, Lee S, Green BT, Lindstrom J, Kem W. Andrud K, et al. Mar Drugs. 2019 Oct 29;17(11):614. doi: 10.3390/md17110614. Mar Drugs. 2019. PMID: 31671780 Free PMC article.

10

Hydroxy metabolites of the Alzheimer's drug candidate 3-[(2,4-dimethoxy)benzylidene]-anabaseine dihydrochloride (GTS-21): their molecular properties, interactions with brain nicotinic receptors, and brain penetration.

Kem WR, Mahnir VM, Prokai L, Papke RL, Cao X, LeFrancois S, Wildeboer K, Prokai-Tatrai K, Porter-Papke J, Soti F. Kem WR, et al. Among authors: mahnir vm. Mol Pharmacol. 2004 Jan;65(1):56-67. doi: 10.1124/mol.65.1.56. Mol Pharmacol. 2004. PMID: 14722237

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