Jansen G - Search Results

1

Circumvention of methotrexate resistance in childhood leukemia subtypes by rationally designed antifolates.

Rots MG, Pieters R, Peters GJ, van Zantwijk CH, Mauritz R, Noordhuis P, Willey JC, Hählen K, Creutzig U, Janka-Schaub G, Kaspers GJ, Veerman AJ, Jansen G. Rots MG, et al. Among authors: jansen g. Blood. 1999 Nov 1;94(9):3121-8. Blood. 1999. PMID: 10556198 Free article.

2

Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma.

Braakhuis BJ, Jansen G, Noordhuis P, Kegel A, Peters GJ. Braakhuis BJ, et al. Among authors: jansen g. Biochem Pharmacol. 1993 Dec 14;46(12):2155-61. doi: 10.1016/0006-2952(93)90604-u. Biochem Pharmacol. 1993. PMID: 7506025

3

Leucovorin rescue of human cancer and bone marrow cells following edatrexate or methotrexate.

Jolivet J, Jansen G, Peters GJ, Pinard MF, Schornagel JH. Jolivet J, et al. Among authors: jansen g. Biochem Pharmacol. 1994 Feb 11;47(4):659-65. doi: 10.1016/0006-2952(94)90128-7. Biochem Pharmacol. 1994. PMID: 7510479

4

Functional activity of the reduced folate carrier in KB, MA104, and IGROV-I cells expressing folate-binding protein.

Westerhof GR, Rijnboutt S, Schornagel JH, Pinedo HM, Peters GJ, Jansen G. Westerhof GR, et al. Among authors: jansen g. Cancer Res. 1995 Sep 1;55(17):3795-802. Cancer Res. 1995. PMID: 7641196

5

Variable pharmacodynamics of antifolates in squamous cell carcinoma of the head and neck.

Braakhuis BJ, Jansen G, Peters GJ. Braakhuis BJ, et al. Among authors: jansen g. Adv Exp Med Biol. 1993;338:671-4. doi: 10.1007/978-1-4615-2960-6_139. Adv Exp Med Biol. 1993. PMID: 8304205 No abstract available.

6

Cross-resistance to antifolates in multidrug resistant cell lines with P-glycoprotein or multidrug resistance protein expression.

van Triest B, Pinedo HM, Telleman F, van der Wilt CL, Jansen G, Peters GJ. van Triest B, et al. Among authors: jansen g. Biochem Pharmacol. 1997 Jun 15;53(12):1855-66. doi: 10.1016/s0006-2952(97)82448-3. Biochem Pharmacol. 1997. PMID: 9256160

7

Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.

Jansen G, Mauritz RM, Assaraf YG, Sprecher H, Drori S, Kathmann I, Westerhof GR, Priest DG, Bunni M, Pinedo HM, Schornagel JH, Peters GJ. Jansen G, et al. Adv Enzyme Regul. 1997;37:59-76. doi: 10.1016/s0065-2571(96)00012-x. Adv Enzyme Regul. 1997. PMID: 9381986

8

Determinants of the therapeutic efficacy of thymidylate synthase inhibitors.

Peters GJ, Kuiper CM, van Triest B, Backus H, van der Wilt CL, van Laar JA, Jansen G, van Groeningen CJ, Pinedo HM. Peters GJ, et al. Among authors: jansen g. Adv Exp Med Biol. 1998;431:699-704. doi: 10.1007/978-1-4615-5381-6_135. Adv Exp Med Biol. 1998. PMID: 9598155 No abstract available.

9

Ex vivo activity of methotrexate versus novel antifolate inhibitors of dihydrofolate reductase and thymidylate synthase against childhood leukemia cells.

Mauritz R, Bekkenk MW, Rots MG, Pieters R, Mini E, van Zantwijk CH, Veerman AJ, Peters GJ, Jansen G. Mauritz R, et al. Among authors: jansen g. Clin Cancer Res. 1998 Oct;4(10):2399-410. Clin Cancer Res. 1998. PMID: 9796971

10

A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.

Jansen G, Mauritz R, Drori S, Sprecher H, Kathmann I, Bunni M, Priest DG, Noordhuis P, Schornagel JH, Pinedo HM, Peters GJ, Assaraf YG. Jansen G, et al. J Biol Chem. 1998 Nov 13;273(46):30189-98. doi: 10.1074/jbc.273.46.30189. J Biol Chem. 1998. PMID: 9804775 Free article.

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