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Stabilization of the Fv fragments in recombinant immunotoxins by disulfide bonds engineered into conserved framework regions.
Reiter Y, Brinkmann U, Kreitman RJ, Jung SH, Lee B, Pastan I. Reiter Y, et al. Among authors: pastan i. Biochemistry. 1994 May 10;33(18):5451-9. doi: 10.1021/bi00184a014. Biochemistry. 1994. PMID: 7910034
We have recently described one example of a recombinant immunotoxin, B3(dsFv)-PE38KDEL, that is composed of such a dsFv connected to a truncated form of Pseudomonas exotoxin [Brinkmann, U., Reiter, Y., Jung, S.-H., Lee, B., & Pastan, I. (1993) Proc. Natl. Acad. …
We have recently described one example of a recombinant immunotoxin, B3(dsFv)-PE38KDEL, that is composed of such a dsFv connected to a trunc …
1,282 results