Cahard D - Search Results

1

Activities of masked 2',3'-dideoxynucleoside monophosphate derivatives against human immunodeficiency virus in resting macrophages.

Aquaro S, Wedgwood O, Yarnold C, Cahard D, Pathinara R, McGuigan C, Calio' R, de Clercq E, Balzarini J, Perno CF. Aquaro S, et al. Among authors: cahard d. Antimicrob Agents Chemother. 2000 Jan;44(1):173-7. doi: 10.1128/AAC.44.1.173-177.2000. Antimicrob Agents Chemother. 2000. PMID: 10602742 Free PMC article.

2

Marked inhibitory activity of masked aryloxy aminoacyl phosphoramidate derivatives of dideoxynucleoside analogues against visna virus infection.

Balzarini J, Cahard D, Wedgwood O, Salgado A, Velázquez S, Yarnold CJ, De Clercq E, McGuigan C, Thormar H. Balzarini J, et al. Among authors: cahard d. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Apr 1;17(4):296-302. doi: 10.1097/00042560-199804010-00002. J Acquir Immune Defic Syndr Hum Retrovirol. 1998. PMID: 9525429

3

Synthesis, anti-human immunodeficiency virus activity and esterase lability of some novel carboxylic ester-modified phosphoramidate derivatives of stavudine (d4T).

McGuigan C, Sutton PW, Cahard D, Turner K, O'Leary G, Wang Y, Gumbleton M, De Clercq E, Balzarini J. McGuigan C, et al. Among authors: cahard d. Antivir Chem Chemother. 1998 Nov;9(6):473-9. doi: 10.1177/095632029800900603. Antivir Chem Chemother. 1998. PMID: 9865385

4

Mechanism of anti-HIV action of masked alaninyl d4T-MP derivatives.

Balzarini J, Karlsson A, Aquaro S, Perno CF, Cahard D, Naesens L, De Clercq E, McGuigan C. Balzarini J, et al. Among authors: cahard d. Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7295-9. doi: 10.1073/pnas.93.14.7295. Proc Natl Acad Sci U S A. 1996. PMID: 8692986 Free PMC article.

5

Aryl phosphoramidate derivatives of d4T have improved anti-HIV efficacy in tissue culture and may act by the generation of a novel intracellular metabolite.

McGuigan C, Cahard D, Sheeka HM, De Clercq E, Balzarini J. McGuigan C, et al. Among authors: cahard d. J Med Chem. 1996 Apr 12;39(8):1748-53. doi: 10.1021/jm950605j. J Med Chem. 1996. PMID: 8648614

6

Antiretrovirus specificity and intracellular metabolism of 2',3' -didehydro-2',3'-dideoxythymidine (stavudine) and its 5'-monophosphate triester prodrug So324.

Balzarini J, Egberink H, Hartmann K, Cahard D, Vahlenkamp T, Thormar H, De Clercq E, McGuigan C. Balzarini J, et al. Among authors: cahard d. Mol Pharmacol. 1996 Nov;50(5):1207-13. Mol Pharmacol. 1996. PMID: 8913352

7

Metabolism and anti-HIV activity of phosphoramidate derivatives of D4T-MP with variations in the amino acid moiety.

Naesens L, Cahard D, Salgado A, Bidois L, De Clercq E, McGuigan C, Balzarini J. Naesens L, et al. Among authors: cahard d. Adv Exp Med Biol. 1998;431:753-7. doi: 10.1007/978-1-4615-5381-6_144. Adv Exp Med Biol. 1998. PMID: 9598164

8

A QSAR study investigating the effect of L-alanine ester variation on the anti-HIV activity of some phosphoramidate derivatives of d4T.

Knaggs MH, McGuigan C, Harris SA, Heshmati P, Cahard D, Gilbert IH, Balzarini J. Knaggs MH, et al. Among authors: cahard d. Bioorg Med Chem Lett. 2000 Sep 18;10(18):2075-8. doi: 10.1016/s0960-894x(00)00397-8. Bioorg Med Chem Lett. 2000. PMID: 10999474

9

Phosphoramidate derivatives of d4T as inhibitors of HIV: the effect of amino acid variation.

McGuigan C, Tsang HW, Cahard D, Turner K, Velazquez S, Salgado A, Bidois L, Naesens L, De Clercq E, Balzarini J. McGuigan C, et al. Among authors: cahard d. Antiviral Res. 1997 Aug;35(3):195-204. doi: 10.1016/s0166-3542(97)00029-6. Antiviral Res. 1997. PMID: 9298759

10

Lactate cannot substitute for alanine in d4T-based anti-HIV nucleotide prodrugs--despite efficient esterase-mediated hydrolysis.

McGuigan C, Cahard D, Ballatore C, Siddiqui A, De Clercq E, Balzarini J. McGuigan C, et al. Among authors: cahard d. Bioorg Med Chem Lett. 1998 Nov 3;8(21):2949-54. doi: 10.1016/S0960-894X(98)00530-7. Bioorg Med Chem Lett. 1998. PMID: 9873653

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

72 results

Search Page

Filters