de Clercq E - Search Results

1

Activities of masked 2',3'-dideoxynucleoside monophosphate derivatives against human immunodeficiency virus in resting macrophages.

Aquaro S, Wedgwood O, Yarnold C, Cahard D, Pathinara R, McGuigan C, Calio' R, de Clercq E, Balzarini J, Perno CF. Aquaro S, et al. Among authors: de clercq e. Antimicrob Agents Chemother. 2000 Jan;44(1):173-7. doi: 10.1128/AAC.44.1.173-177.2000. Antimicrob Agents Chemother. 2000. PMID: 10602742 Free PMC article.

2

Different pattern of activity of inhibitors of the human immunodeficiency virus in lymphocytes and monocyte/macrophages.

Perno CF, Yarchoan R, Balzarini J, Bergamini A, Milanese G, Pauwels R, De Clercq E, Rocchi G, Calio R. Perno CF, et al. Among authors: de clercq e. Antiviral Res. 1992 Apr;17(4):289-304. doi: 10.1016/0166-3542(92)90024-y. Antiviral Res. 1992. PMID: 1322645

3

Immunomodulatory activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA), a potent anti-HIV nucleotide analogue, on in vivo murine models.

Del Gobbo V, Foli A, Balzarini J, De Clercq E, Balestra E, Villani N, Marini S, Perno CF, Calio R. Del Gobbo V, et al. Among authors: de clercq e. Antiviral Res. 1991 Jul;16(1):65-75. doi: 10.1016/0166-3542(91)90059-z. Antiviral Res. 1991. PMID: 1723264

4

Activity of acyclic nucleoside phosphonate analogues against human immunodeficiency virus in monocyte/macrophages and peripheral blood lymphocytes.

Balzarini J, Perno CF, Schols D, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Biochem Biophys Res Commun. 1991 Jul 15;178(1):329-35. doi: 10.1016/0006-291x(91)91818-w. Biochem Biophys Res Commun. 1991. PMID: 2069572

5

Phosphonylmethoxyethyl purine derivatives, a new class of anti-human immunodeficiency virus agents.

Pauwels R, Balzarini J, Schols D, Baba M, Desmyter J, Rosenberg I, Holy A, De Clercq E. Pauwels R, et al. Among authors: de clercq e. Antimicrob Agents Chemother. 1988 Jul;32(7):1025-30. doi: 10.1128/AAC.32.7.1025. Antimicrob Agents Chemother. 1988. PMID: 2847636 Free PMC article.

6

Ribavirin antagonizes inhibitory effects of pyrimidine 2',3'-dideoxynucleosides but enhances inhibitory effects of purine 2',3'-dideoxynucleosides on replication of human immunodeficiency virus in vitro.

Baba M, Pauwels R, Balzarini J, Herdewijn P, De Clercq E, Desmyter J. Baba M, et al. Among authors: de clercq e. Antimicrob Agents Chemother. 1987 Oct;31(10):1613-7. doi: 10.1128/AAC.31.10.1613. Antimicrob Agents Chemother. 1987. PMID: 3435108 Free PMC article.

7

Differential activities of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives against different human immunodeficiency virus type 1 mutant strains.

Balzarini J, Baba M, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Antimicrob Agents Chemother. 1995 Apr;39(4):998-1002. doi: 10.1128/AAC.39.4.998. Antimicrob Agents Chemother. 1995. PMID: 7540384 Free PMC article.

8

9-(2-Phosphonylmethoxyethyl) adenine increases the survival of influenza virus-infected mice by an enhancement of the immune system.

Villani N, Caliò R, Balestra E, Balzarini J, De Clercq E, Fabrizi E, Perno CF, Del Gobbo V. Villani N, et al. Among authors: de clercq e. Antiviral Res. 1994 Oct;25(2):81-9. doi: 10.1016/0166-3542(94)90098-1. Antiviral Res. 1994. PMID: 7847879

9

Knocking out human immunodeficiency virus through non-nucleoside reverse transcriptase inhibitors used as single agents or in combinations: a paradigm for the cure of AIDS?

De Clercq E, Balzarini J. De Clercq E, et al. Farmaco. 1995 Nov;50(11):735-47. Farmaco. 1995. PMID: 8593170 Review.

10

Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus.

Balzarini J, Kruining J, Wedgwood O, Pannecouque C, Aquaro S, Perno CF, Naesens L, Witvrouw M, Heijtink R, De Clercq E, McGuigan C. Balzarini J, et al. Among authors: de clercq e. FEBS Lett. 1997 Jun 30;410(2-3):324-8. doi: 10.1016/s0014-5793(97)00616-9. FEBS Lett. 1997. PMID: 9237655 Free article.

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