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A neural pathway controlling motivation to exert effort.
Proulx CD, Aronson S, Milivojevic D, Molina C, Loi A, Monk B, Shabel SJ, Malinow R. Proulx CD, et al. Among authors: malinow r. Proc Natl Acad Sci U S A. 2018 May 29;115(22):5792-5797. doi: 10.1073/pnas.1801837115. Epub 2018 May 11. Proc Natl Acad Sci U S A. 2018. PMID: 29752382 Free PMC article.
Stress transforms lateral habenula reward responses into punishment signals.
Shabel SJ, Wang C, Monk B, Aronson S, Malinow R. Shabel SJ, et al. Among authors: malinow r. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12488-12493. doi: 10.1073/pnas.1903334116. Epub 2019 May 31. Proc Natl Acad Sci U S A. 2019. PMID: 31152135 Free PMC article.
Neuronal activity in the lateral habenula (LHb), a brain region implicated in depression [C. D. Proulx, O. Hikosaka, R. Malinow, Nat. Neurosci. 17, 1146-1152 (2014)], decreases during reward and increases during punishment or reward omission [M. ...
Neuronal activity in the lateral habenula (LHb), a brain region implicated in depression [C. D. Proulx, O. Hikosaka, R. Malinow …
133 results