Molkentin JD - Search Results

1

Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy.

Taigen T, De Windt LJ, Lim HW, Molkentin JD. Taigen T, et al. Among authors: molkentin jd. Proc Natl Acad Sci U S A. 2000 Feb 1;97(3):1196-201. doi: 10.1073/pnas.97.3.1196. Proc Natl Acad Sci U S A. 2000. PMID: 10655507 Free PMC article.

2

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy.

Molkentin JD, Lu JR, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, Olson EN. Molkentin JD, et al. Cell. 1998 Apr 17;93(2):215-28. doi: 10.1016/s0092-8674(00)81573-1. Cell. 1998. PMID: 9568714 Free PMC article.

3

Prevention of cardiac hypertrophy in mice by calcineurin inhibition.

Sussman MA, Lim HW, Gude N, Taigen T, Olson EN, Robbins J, Colbert MC, Gualberto A, Wieczorek DF, Molkentin JD. Sussman MA, et al. Among authors: molkentin jd. Science. 1998 Sep 11;281(5383):1690-3. doi: 10.1126/science.281.5383.1690. Science. 1998. PMID: 9733519

4

Calcineurin and human heart failure.

Lim HW, Molkentin JD. Lim HW, et al. Among authors: molkentin jd. Nat Med. 1999 Mar;5(3):246-7. doi: 10.1038/6430. Nat Med. 1999. PMID: 10086361 No abstract available.

5

Pathogenesis of dilated cardiomyopathy: molecular, structural, and population analyses in tropomodulin-overexpressing transgenic mice.

Sussman MA, Welch S, Gude N, Khoury PR, Daniels SR, Kirkpatrick D, Walsh RA, Price RL, Lim HW, Molkentin JD. Sussman MA, et al. Among authors: molkentin jd. Am J Pathol. 1999 Dec;155(6):2101-13. doi: 10.1016/S0002-9440(10)65528-9. Am J Pathol. 1999. PMID: 10595939 Free PMC article.

6

Direct activation of a GATA6 cardiac enhancer by Nkx2.5: evidence for a reinforcing regulatory network of Nkx2.5 and GATA transcription factors in the developing heart.

Molkentin JD, Antos C, Mercer B, Taigen T, Miano JM, Olson EN. Molkentin JD, et al. Dev Biol. 2000 Jan 15;217(2):301-9. doi: 10.1006/dbio.1999.9544. Dev Biol. 2000. PMID: 10625555 Free article.

7

Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure.

De Windt LJ, Lim HW, Taigen T, Wencker D, Condorelli G, Dorn GW 2nd, Kitsis RN, Molkentin JD. De Windt LJ, et al. Among authors: molkentin jd. Circ Res. 2000 Feb 18;86(3):255-63. doi: 10.1161/01.res.86.3.255. Circ Res. 2000. PMID: 10679475

8

Hypertrophic defect unmasked by calcineurin expression in asymptomatic tropomodulin overexpressing transgenic mice.

Sussman MA, Welch S, Walker A, Klevitsky R, Hewett TE, Witt SA, Kimball TR, Price R, Lim HW, Molkentin JD. Sussman MA, et al. Among authors: molkentin jd. Cardiovasc Res. 2000 Apr;46(1):90-101. doi: 10.1016/s0008-6363(99)00422-8. Cardiovasc Res. 2000. PMID: 10727657

9

Reversal of cardiac hypertrophy in transgenic disease models by calcineurin inhibition.

Lim HW, De Windt LJ, Mante J, Kimball TR, Witt SA, Sussman MA, Molkentin JD. Lim HW, et al. Among authors: molkentin jd. J Mol Cell Cardiol. 2000 Apr;32(4):697-709. doi: 10.1006/jmcc.2000.1113. J Mol Cell Cardiol. 2000. PMID: 10756124

10

Calcineurin promotes protein kinase C and c-Jun NH2-terminal kinase activation in the heart. Cross-talk between cardiac hypertrophic signaling pathways.

De Windt LJ, Lim HW, Haq S, Force T, Molkentin JD. De Windt LJ, et al. Among authors: molkentin jd. J Biol Chem. 2000 May 5;275(18):13571-9. doi: 10.1074/jbc.275.18.13571. J Biol Chem. 2000. PMID: 10788473 Free article.

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