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Dominant-negative inhibition of prion replication in transgenic mice.
Perrier V, Kaneko K, Safar J, Vergara J, Tremblay P, DeArmond SJ, Cohen FE, Prusiner SB, Wallace AC. Perrier V, et al. Among authors: tremblay p. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13079-84. doi: 10.1073/pnas.182425299. Epub 2002 Sep 23. Proc Natl Acad Sci U S A. 2002. PMID: 12271119 Free PMC article.
A transmembrane form of the prion protein in neurodegenerative disease.
Hegde RS, Mastrianni JA, Scott MR, DeFea KA, Tremblay P, Torchia M, DeArmond SJ, Prusiner SB, Lingappa VR. Hegde RS, et al. Among authors: tremblay p. Science. 1998 Feb 6;279(5352):827-34. doi: 10.1126/science.279.5352.827. Science. 1998. PMID: 9452375
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel.
Moore RC, Lee IY, Silverman GL, Harrison PM, Strome R, Heinrich C, Karunaratne A, Pasternak SH, Chishti MA, Liang Y, Mastrangelo P, Wang K, Smit AF, Katamine S, Carlson GA, Cohen FE, Prusiner SB, Melton DW, Tremblay P, Hood LE, Westaway D. Moore RC, et al. Among authors: tremblay p. J Mol Biol. 1999 Oct 1;292(4):797-817. doi: 10.1006/jmbi.1999.3108. J Mol Biol. 1999. PMID: 10525406
Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene.
Korth C, Kaneko K, Groth D, Heye N, Telling G, Mastrianni J, Parchi P, Gambetti P, Will R, Ironside J, Heinrich C, Tremblay P, DeArmond SJ, Prusiner SB. Korth C, et al. Among authors: tremblay p. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4784-9. doi: 10.1073/pnas.2627989100. Epub 2003 Apr 8. Proc Natl Acad Sci U S A. 2003. PMID: 12684540 Free PMC article.
Prion clearance in bigenic mice.
Safar JG, DeArmond SJ, Kociuba K, Deering C, Didorenko S, Bouzamondo-Bernstein E, Prusiner SB, Tremblay P. Safar JG, et al. Among authors: tremblay p. J Gen Virol. 2005 Oct;86(Pt 10):2913-2923. doi: 10.1099/vir.0.80947-0. J Gen Virol. 2005. PMID: 16186247
422 results