van den Broek W - Search Results

1

Constitutive and regulated modes of splicing produce six major myotonic dystrophy protein kinase (DMPK) isoforms with distinct properties.

Groenen PJ, Wansink DG, Coerwinkel M, van den Broek W, Jansen G, Wieringa B. Groenen PJ, et al. Among authors: van den broek w. Hum Mol Genet. 2000 Mar 1;9(4):605-16. doi: 10.1093/hmg/9.4.605. Hum Mol Genet. 2000. PMID: 10699184

2

Inactivation of Apoe and Apoc1 by two consecutive rounds of gene targeting: effects on mRNA expression levels of gene cluster members.

van Ree JH, van den Broek WJ, van der Zee A, Dahlmans VE, Wieringa B, Frants RR, Havekes LM, Hofker MH. van Ree JH, et al. Among authors: van den broek wj, van der zee a. Hum Mol Genet. 1995 Aug;4(8):1403-9. doi: 10.1093/hmg/4.8.1403. Hum Mol Genet. 1995. PMID: 7581381 Free article.

3

Diet-induced hypercholesterolemia and atherosclerosis in heterozygous apolipoprotein E-deficient mice.

van Ree JH, van den Broek WJ, Dahlmans VE, Groot PH, Vidgeon-Hart M, Frants RR, Wieringa B, Havekes LM, Hofker MH. van Ree JH, et al. Among authors: van den broek wj. Atherosclerosis. 1994 Nov;111(1):25-37. doi: 10.1016/0021-9150(94)90188-0. Atherosclerosis. 1994. PMID: 7840811

4

Increased response to cholesterol feeding in apolipoprotein C1-deficient mice.

van Ree JH, Hofker MH, van den Broek WJ, van Deursen JM, van der Boom H, Frants RR, Wieringa B, Havekes LM. van Ree JH, et al. Among authors: van den broek wj, van deursen jm, van der boom h. Biochem J. 1995 Feb 1;305 ( Pt 3)(Pt 3):905-11. doi: 10.1042/bj3050905. Biochem J. 1995. PMID: 7848292 Free PMC article.

5

Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.

Jansen G, Groenen PJ, Bächner D, Jap PH, Coerwinkel M, Oerlemans F, van den Broek W, Gohlsch B, Pette D, Plomp JJ, Molenaar PC, Nederhoff MG, van Echteld CJ, Dekker M, Berns A, Hameister H, Wieringa B. Jansen G, et al. Among authors: van echteld cj, van den broek w. Nat Genet. 1996 Jul;13(3):316-24. doi: 10.1038/ng0796-316. Nat Genet. 1996. PMID: 8673131 Free article.

6

Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins.

van den Broek WJ, Nelen MR, Wansink DG, Coerwinkel MM, te Riele H, Groenen PJ, Wieringa B. van den Broek WJ, et al. Hum Mol Genet. 2002 Jan 15;11(2):191-8. doi: 10.1093/hmg/11.2.191. Hum Mol Genet. 2002. PMID: 11809728

7

Transgenic overexpression of human DMPK accumulates into hypertrophic cardiomyopathy, myotonic myopathy and hypotension traits of myotonic dystrophy.

O'Cochlain DF, Perez-Terzic C, Reyes S, Kane GC, Behfar A, Hodgson DM, Strommen JA, Liu XK, van den Broek W, Wansink DG, Wieringa B, Terzic A. O'Cochlain DF, et al. Among authors: van den broek w. Hum Mol Genet. 2004 Oct 15;13(20):2505-18. doi: 10.1093/hmg/ddh266. Epub 2004 Aug 18. Hum Mol Genet. 2004. PMID: 15317754

8

Fen1 does not control somatic hypermutability of the (CTG)(n)*(CAG)(n) repeat in a knock-in mouse model for DM1.

van den Broek WJ, Nelen MR, van der Heijden GW, Wansink DG, Wieringa B. van den Broek WJ, et al. Among authors: van der heijden gw. FEBS Lett. 2006 Oct 2;580(22):5208-14. doi: 10.1016/j.febslet.2006.08.059. Epub 2006 Sep 5. FEBS Lett. 2006. PMID: 16978612 Free article.

9

Somatic CTG*CAG repeat instability in a mouse model for myotonic dystrophy type 1 is associated with changes in cell nuclearity and DNA ploidy.

van den Broek WJ, Wansink DG, Wieringa B. van den Broek WJ, et al. BMC Mol Biol. 2007 Jul 23;8:61. doi: 10.1186/1471-2199-8-61. BMC Mol Biol. 2007. PMID: 17645799 Free PMC article.

10

Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy.

Mulders SA, van den Broek WJ, Wheeler TM, Croes HJ, van Kuik-Romeijn P, de Kimpe SJ, Furling D, Platenburg GJ, Gourdon G, Thornton CA, Wieringa B, Wansink DG. Mulders SA, et al. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13915-20. doi: 10.1073/pnas.0905780106. Epub 2009 Aug 10. Proc Natl Acad Sci U S A. 2009. PMID: 19667189 Free PMC article.

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