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The angiotensin II receptor antagonist valsartan inhibits endothelin 1-induced vasoconstriction in the skin microcirculation in humans in vivo: influence of the G-protein beta3 subunit (GNB3) C825T polymorphism.
Mitchell A, Rushentsova U, Siffert W, Philipp T, Wenzel RR. Mitchell A, et al. Among authors: wenzel rr. Clin Pharmacol Ther. 2006 Mar;79(3):274-81. doi: 10.1016/j.clpt.2005.11.008. Epub 2006 Feb 3. Clin Pharmacol Ther. 2006. PMID: 16513451 Clinical Trial.
Avosentan reduces albumin excretion in diabetics with macroalbuminuria.
Wenzel RR, Littke T, Kuranoff S, Jürgens C, Bruck H, Ritz E, Philipp T, Mitchell A; SPP301 (Avosentan) Endothelin Antagonist Evaluation in Diabetic Nephropathy Study Investigators. Wenzel RR, et al. J Am Soc Nephrol. 2009 Mar;20(3):655-64. doi: 10.1681/ASN.2008050482. Epub 2009 Jan 14. J Am Soc Nephrol. 2009. PMID: 19144760 Free PMC article. Clinical Trial.
697 results