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Page 1
Design and SAR of novel potassium channel openers targeted for urge urinary incontinence. 1. N-Cyanoguanidine bioisosteres possessing in vivo bladder selectivity.
Butera JA, Antane MM, Antane SA, Argentieri TM, Freeden C, Graceffa RF, Hirth BH, Jenkins D, Lennox JR, Matelan E, Norton NW, Quagliato D, Sheldon JH, Spinelli W, Warga D, Wojdan A, Woods M. Butera JA, et al. Among authors: antane sa. J Med Chem. 2000 Mar 23;43(6):1187-202. doi: 10.1021/jm9905099. J Med Chem. 2000. PMID: 10737752
Pyrido[2,3-d]pyrimidine angiotensin II antagonists.
Ellingboe JW, Antane M, Nguyen TT, Collini MD, Antane S, Bender R, Hartupee D, White V, McCallum J, Park CH, et al. Ellingboe JW, et al. J Med Chem. 1994 Feb 18;37(4):542-50. doi: 10.1021/jm00030a013. J Med Chem. 1994. PMID: 8120871
3-(Arylsulfonyl)-1-(azacyclyl)-1H-indoles are 5-HT(6) receptor modulators.
Bernotas RC, Antane S, Shenoy R, Le VD, Chen P, Harrison BL, Robichaud AJ, Zhang GM, Smith D, Schechter LE. Bernotas RC, et al. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1657-60. doi: 10.1016/j.bmcl.2010.01.073. Epub 2010 Jan 21. Bioorg Med Chem Lett. 2010. PMID: 20138763
Pulvinones as bacterial cell wall biosynthesis inhibitors.
Antane S, Caufield CE, Hu W, Keeney D, Labthavikul P, Morris K, Naughton SM, Petersen PJ, Rasmussen BA, Singh G, Yang Y. Antane S, et al. Bioorg Med Chem Lett. 2006 Jan 1;16(1):176-80. doi: 10.1016/j.bmcl.2005.09.021. Epub 2005 Oct 10. Bioorg Med Chem Lett. 2006. PMID: 16216496
1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-pyrrolopyridines are 5-HT(6) receptor ligands.
Bernotas RC, Antane SA, Lenicek SE, Haydar SN, Robichaud AJ, Harrison BL, Zhang GM, Smith D, Coupet J, Schechter LE. Bernotas RC, et al. Among authors: antane sa. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6935-8. doi: 10.1016/j.bmcl.2009.10.067. Epub 2009 Oct 20. Bioorg Med Chem Lett. 2009. PMID: 19884004