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Complementary dual-virus strategy drives synthetic target and cognate T-cell engager expression for endogenous-antigen agnostic immunotherapy.
Taha Z, Crupi MJF, Alluqmani N, MacKenzie D, Vallati S, Whelan JT, Fareez F, Alwithenani A, Petryk J, Chen A, Spinelli MM, Ng K, Sobh J, de Souza CT, Bharadwa PR, Lee TKH, Thomas DA, Huang BZ, Kassas O, Poutou J, Gilchrist VH, Boulton S, Thomson M, Marius R, Hooshyar M, McComb S, Arulanandam R, Ilkow CS, Bell JC, Diallo JS. Taha Z, et al. Among authors: de souza ct. Nat Commun. 2024 Aug 23;15(1):7267. doi: 10.1038/s41467-024-51498-0. Nat Commun. 2024. PMID: 39179564 Free PMC article.
Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy via lipid modulation of the tumor microenvironment.
Surendran A, Jamalkhah M, Poutou J, Birtch R, Lawson C, Dave J, Crupi MJF, Mayer J, Taylor V, Petryk J, de Souza CT, Moodie N, Billingsley JL, Austin B, Cormack N, Blamey N, Rezaei R, McCloskey CW, Fekete EEF, Birdi HK, Neault S, Jamieson TR, Wylie B, Tucker S, Azad T, Vanderhyden B, Tai LH, Bell JC, Ilkow CS. Surendran A, et al. Among authors: de souza ct. Front Immunol. 2023 Mar 10;14:1099459. doi: 10.3389/fimmu.2023.1099459. eCollection 2023. Front Immunol. 2023. PMID: 36969187 Free PMC article.
CEACAM1 is a direct SOX10 target and inhibits melanoma immune infiltration and stemness.
Abou-Hamad J, Hodgins JJ, de Souza CT, Garland B, Labrèche C, Marotel M, Gibson C, Delisle S, Pascoal J, Auer RC, Ardolino M, Sabourin LA. Abou-Hamad J, et al. Among authors: de souza ct. iScience. 2022 Nov 7;25(12):105524. doi: 10.1016/j.isci.2022.105524. eCollection 2022 Dec 22. iScience. 2022. PMID: 36437876 Free PMC article.
In vivo and in silico approaches to assess surface water genotoxicity from Tocantins River, in the cities of Porto Nacional and Palmas, Brazil.
Neto JLS, de Carli RF, Lehmann M, de Souza CT, Niekraszewicz LAB, Dias JF, da Silva FR, da Silva J, Dihl RR. Neto JLS, et al. Among authors: de souza ct. J Environ Sci Health C Toxicol Carcinog. 2022;40(1):27-45. doi: 10.1080/26896583.2021.2014278. Epub 2022 Jan 4. J Environ Sci Health C Toxicol Carcinog. 2022. PMID: 35895928
155 results