Saxton WM - Search Results

1

A kinesin mutation that uncouples motor domains and desensitizes the gamma-phosphate sensor.

Brendza KM, Sontag CA, Saxton WM, Gilbert SP. Brendza KM, et al. Among authors: saxton wm. J Biol Chem. 2000 Jul 21;275(29):22187-95. doi: 10.1074/jbc.M001124200. J Biol Chem. 2000. PMID: 10767290 Free PMC article.

2

Lethal kinesin mutations reveal amino acids important for ATPase activation and structural coupling.

Brendza KM, Rose DJ, Gilbert SP, Saxton WM. Brendza KM, et al. Among authors: saxton wm. J Biol Chem. 1999 Oct 29;274(44):31506-14. doi: 10.1074/jbc.274.44.31506. J Biol Chem. 1999. PMID: 10531353 Free PMC article.

3

Three routes to suppression of the neurodegenerative phenotypes caused by kinesin heavy chain mutations.

Djagaeva I, Rose DJ, Lim A, Venter CE, Brendza KM, Moua P, Saxton WM. Djagaeva I, et al. Among authors: saxton wm. Genetics. 2012 Sep;192(1):173-83. doi: 10.1534/genetics.112.140798. Epub 2012 Jun 19. Genetics. 2012. PMID: 22714410 Free PMC article.

4

Microtubule-kinesin interface mutants reveal a site critical for communication.

Klumpp LM, Brendza KM, Gatial JE 3rd, Hoenger A, Saxton WM, Gilbert SP. Klumpp LM, et al. Among authors: saxton wm. Biochemistry. 2004 Mar 16;43(10):2792-803. doi: 10.1021/bi035830e. Biochemistry. 2004. PMID: 15005614 Free PMC article.

5

A "slow" homotetrameric kinesin-related motor protein purified from Drosophila embryos.

Cole DG, Saxton WM, Sheehan KB, Scholey JM. Cole DG, et al. Among authors: saxton wm. J Biol Chem. 1994 Sep 16;269(37):22913-6. J Biol Chem. 1994. PMID: 8083185 Free PMC article.

6

Kinesin heavy chain is essential for viability and neuromuscular functions in Drosophila, but mutants show no defects in mitosis.

Saxton WM, Hicks J, Goldstein LS, Raff EC. Saxton WM, et al. Cell. 1991 Mar 22;64(6):1093-102. doi: 10.1016/0092-8674(91)90264-y. Cell. 1991. PMID: 1825937

7

Kinesin-1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons.

Pilling AD, Horiuchi D, Lively CM, Saxton WM. Pilling AD, et al. Among authors: saxton wm. Mol Biol Cell. 2006 Apr;17(4):2057-68. doi: 10.1091/mbc.e05-06-0526. Epub 2006 Feb 8. Mol Biol Cell. 2006. PMID: 16467387 Free PMC article.

8

Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides.

Barkus RV, Klyachko O, Horiuchi D, Dickson BJ, Saxton WM. Barkus RV, et al. Among authors: saxton wm. Mol Biol Cell. 2008 Jan;19(1):274-83. doi: 10.1091/mbc.e07-03-0261. Epub 2007 Nov 7. Mol Biol Cell. 2008. PMID: 17989365 Free PMC article.

9

Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila.

Hurd DD, Saxton WM. Hurd DD, et al. Among authors: saxton wm. Genetics. 1996 Nov;144(3):1075-85. doi: 10.1093/genetics/144.3.1075. Genetics. 1996. PMID: 8913751 Free PMC article.

10

Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport.

Martin M, Iyadurai SJ, Gassman A, Gindhart JG Jr, Hays TS, Saxton WM. Martin M, et al. Among authors: saxton wm. Mol Biol Cell. 1999 Nov;10(11):3717-28. doi: 10.1091/mbc.10.11.3717. Mol Biol Cell. 1999. PMID: 10564267 Free PMC article.

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