Schick C - Search Results

1

Development of specific monoclonal antibodies and a sensitive discriminatory immunoassay for the circulating tumor markers SCCA1 and SCCA2.

Cataltepe S, Schick C, Luke CJ, Pak SC, Goldfarb D, Chen P, Tanasiyevic MJ, Posner MR, Silverman GA. Cataltepe S, et al. Among authors: schick c. Clin Chim Acta. 2000 May;295(1-2):107-27. doi: 10.1016/s0009-8981(00)00197-2. Clin Chim Acta. 2000. PMID: 10767398

2

SCCA1 and SCCA2 are proteinase inhibitors that map to the serpin cluster at 18q21.3.

Silverman GA, Bartuski AJ, Cataltepe S, Gornstein ER, Kamachi Y, Schick C, Uemura Y. Silverman GA, et al. Among authors: schick c. Tumour Biol. 1998;19(6):480-7. doi: 10.1159/000030041. Tumour Biol. 1998. PMID: 9817977 Review.

3

Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas.

Cataltepe S, Gornstein ER, Schick C, Kamachi Y, Chatson K, Fries J, Silverman GA, Upton MP. Cataltepe S, et al. Among authors: schick c. J Histochem Cytochem. 2000 Jan;48(1):113-22. doi: 10.1177/002215540004800112. J Histochem Cytochem. 2000. PMID: 10653592

4

Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells.

Uemura Y, Pak SC, Luke C, Cataltepe S, Tsu C, Schick C, Kamachi Y, Pomeroy SL, Perlmutter DH, Silverman GA. Uemura Y, et al. Among authors: schick c. Int J Cancer. 2000 Jul 20;89(4):368-77. doi: 10.1002/1097-0215(20000720)89:4<368::aid-ijc9>3.0.co;2-6. Int J Cancer. 2000. PMID: 10956412

5

A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.

Schneider SS, Schick C, Fish KE, Miller E, Pena JC, Treter SD, Hui SM, Silverman GA. Schneider SS, et al. Among authors: schick c. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3147-51. doi: 10.1073/pnas.92.8.3147. Proc Natl Acad Sci U S A. 1995. PMID: 7724531 Free PMC article.

6

Squamous cell carcinoma antigen 2 is a novel serpin that inhibits the chymotrypsin-like proteinases cathepsin G and mast cell chymase.

Schick C, Kamachi Y, Bartuski AJ, Cataltepe S, Schechter NM, Pemberton PA, Silverman GA. Schick C, et al. J Biol Chem. 1997 Jan 17;272(3):1849-55. doi: 10.1074/jbc.272.3.1849. J Biol Chem. 1997. PMID: 8999871 Free article.

7

Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis.

Schick C, Pemberton PA, Shi GP, Kamachi Y, Cataltepe S, Bartuski AJ, Gornstein ER, Brömme D, Chapman HA, Silverman GA. Schick C, et al. Biochemistry. 1998 Apr 14;37(15):5258-66. doi: 10.1021/bi972521d. Biochemistry. 1998. PMID: 9548757

Our previous studies show that SCCA2 inhibits chymotrypsin-like serine proteinases [Schick et al. (1997) J. Biol. Chem. 272, 1849-1855]. We now show that, unlike SCCA2, SCCA1 lacks inhibitory activity against any of the more common types of serine proteinases but is a pote …

Our previous studies show that SCCA2 inhibits chymotrypsin-like serine proteinases [Schick et al. (1997) J. Biol. Chem. 272, 1849-185 …

8

The reactive site loop of the serpin SCCA1 is essential for cysteine proteinase inhibition.

Schick C, Brömme D, Bartuski AJ, Uemura Y, Schechter NM, Silverman GA. Schick C, et al. Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13465-70. doi: 10.1073/pnas.95.23.13465. Proc Natl Acad Sci U S A. 1998. PMID: 9811823 Free PMC article.

9

A murine ortholog of the human serpin SCCA2 maps to chromosome 1 and inhibits chymotrypsin-like serine proteinases.

Bartuski AJ, Kamachi Y, Schick C, Massa H, Trask BJ, Silverman GA. Bartuski AJ, et al. Among authors: schick c. Genomics. 1998 Dec 1;54(2):297-306. doi: 10.1006/geno.1998.5586. Genomics. 1998. PMID: 9828132

10

Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor: a critical role for the P3' proline in facilitating RSL cleavage.

Luke C, Schick C, Tsu C, Whisstock JC, Irving JA, Brömme D, Juliano L, Shi GP, Chapman HA, Silverman GA. Luke C, et al. Among authors: schick c. Biochemistry. 2000 Jun 20;39(24):7081-91. doi: 10.1021/bi000050g. Biochemistry. 2000. PMID: 10852705

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