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Efficacy of triple combination therapy with zidovudine (ZDV) plus zalcitabine (ddC) plus lamivudine (3TC) versus double (ZDV+3TC) combination therapy in patients previously treated with ZDV+ddC.
Ruiz L, Romeu J, Martínez-Picado J, Schmit JC, Vandamme AM, Balagué M, Cabrera C, Puig T, Tural C, Segura A, Sirera G, De Clercq E, Clotet B. Ruiz L, et al. Among authors: schmit jc. AIDS. 1996 Dec;10(14):F61-6. doi: 10.1097/00002030-199612000-00003. AIDS. 1996. PMID: 8970679 Clinical Trial.
Baseline HIV type 1 genotypic resistance to a newly added nucleoside analog is predictive of virologic failure of the new therapy.
Van Vaerenbergh K, Van Laethem K, Van Wijngaerden E, Schmit JC, Schneider F, Ruiz L, Clotet B, Verhofstede C, Van Wanzeele F, Muyldermans G, Simons P, Stuyver L, Hermans P, Evans C, De Clercq E, Desmyter J, Vandamme AM. Van Vaerenbergh K, et al. Among authors: schmit jc. AIDS Res Hum Retroviruses. 2000 Apr 10;16(6):529-37. doi: 10.1089/088922200308945. AIDS Res Hum Retroviruses. 2000. PMID: 10777143
Presence of 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1",2"-oxath iole-2",2"-dioxide) (TSAO)-resistant virus strains in TSAO-inexperienced HIV patients.
Van Laethem K, Schmit JC, Pelemans H, Balzarini J, Witvrouw M, Pérez-Pérez MJ, Camarasa MJ, Esnouf RM, Aquaro S, Cenci A, Perno CF, Hermans P, Sprecher S, Ruiz L, Clotet B, Van Wijngaerden E, Van Ranst M, Desmyter J, De Clercq E, Vandamme AM. Van Laethem K, et al. Among authors: schmit jc. AIDS Res Hum Retroviruses. 2000 Jun 10;16(9):825-33. doi: 10.1089/08892220050042765. AIDS Res Hum Retroviruses. 2000. PMID: 10875608
Phenotypic assays and sequencing are less sensitive than point mutation assays for detection of resistance in mixed HIV-1 genotypic populations.
Van Laethem K, Van Vaerenbergh K, Schmit JC, Sprecher S, Hermans P, De Vroey V, Schuurman R, Harrer T, Witvrouw M, Van Wijngaerden E, Stuyver L, Van Ranst M, Desmyter J, De Clercq E, Vandamme AM. Van Laethem K, et al. Among authors: schmit jc. J Acquir Immune Defic Syndr. 1999 Oct 1;22(2):107-18. doi: 10.1097/00126334-199910010-00001. J Acquir Immune Defic Syndr. 1999. PMID: 10843523
142 results