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A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.
Podrez EA, Poliakov E, Shen Z, Zhang R, Deng Y, Sun M, Finton PJ, Shan L, Febbraio M, Hajjar DP, Silverstein RL, Hoff HF, Salomon RG, Hazen SL. Podrez EA, et al. J Biol Chem. 2002 Oct 11;277(41):38517-23. doi: 10.1074/jbc.M205924200. Epub 2002 Jul 26. J Biol Chem. 2002. PMID: 12145296 Free article.
Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages.
Kunjathoor VV, Febbraio M, Podrez EA, Moore KJ, Andersson L, Koehn S, Rhee JS, Silverstein R, Hoff HF, Freeman MW. Kunjathoor VV, et al. Among authors: podrez ea. J Biol Chem. 2002 Dec 20;277(51):49982-8. doi: 10.1074/jbc.M209649200. Epub 2002 Oct 9. J Biol Chem. 2002. PMID: 12376530 Free article.
Myeloperoxidase-generated oxidants and atherosclerosis.
Podrez EA, Abu-Soud HM, Hazen SL. Podrez EA, et al. Free Radic Biol Med. 2000 Jun 15;28(12):1717-25. doi: 10.1016/s0891-5849(00)00229-x. Free Radic Biol Med. 2000. PMID: 10946213 Review.
92 results