Tufano M - Search Results

1

Synthesis and antibacterial activity of novel 6-O-substituted erythromycin A derivatives.

Clark RF, Ma Z, Wang S, Griesgraber G, Tufano M, Yong H, Li L, Zhang X, Nilius AM, Chu DT, Or YS. Clark RF, et al. Among authors: tufano m. Bioorg Med Chem Lett. 2000 Apr 17;10(8):815-9. doi: 10.1016/s0960-894x(00)00106-2. Bioorg Med Chem Lett. 2000. PMID: 10782693

2

Novel inhibitors of bacterial protein synthesis: structure-activity relationships for 1,8-naphthyridine derivatives incorporating position 3 and 4 variants.

Clark RF, Wang S, Ma Z, Weitzberg M, Motter C, Tufano M, Wagner R, Gu YG, Dandliker PJ, Lerner CG, Chovan LE, Cai Y, Black-Schaefer CL, Lynch L, Kalvin D, Nilius AM, Pratt SD, Soni N, Zhang T, Zhang X, Beutel BA. Clark RF, et al. Among authors: tufano m. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3299-302. doi: 10.1016/j.bmcl.2004.03.091. Bioorg Med Chem Lett. 2004. PMID: 15149694

3

Synthesis and structure-activity relationships of 2-pyridones: a novel series of potent DNA gyrase inhibitors as antibacterial agents.

Li Q, Chu DT, Claiborne A, Cooper CS, Lee CM, Raye K, Berst KB, Donner P, Wang W, Hasvold L, Fung A, Ma Z, Tufano M, Flamm R, Shen LL, Baranowski J, Nilius A, Alder J, Meulbroek J, Marsh K, Crowell D, Hui Y, Seif L, Melcher LM, Plattner JJ, et al. Li Q, et al. Among authors: tufano m. J Med Chem. 1996 Aug 2;39(16):3070-88. doi: 10.1021/jm960207w. J Med Chem. 1996. PMID: 8759628

4

Synthesis and structure-activity relationships of 2-pyridones: II. 8-(Fluoro-substituted pyrrolidinyl)-2-pyridones as antibacterial agents.

Li Q, Wang W, Berst KB, Claiborne A, Hasvold L, Raye K, Tufano M, Nilius A, Shen LL, Flamm R, Alder J, Marsh K, Crowell D, Chu DT, Plattner JJ. Li Q, et al. Among authors: tufano m. Bioorg Med Chem Lett. 1998 Aug 4;8(15):1953-8. doi: 10.1016/s0960-894x(98)00355-2. Bioorg Med Chem Lett. 1998. PMID: 9873465

5

The synthesis and in vitro antibacterial activity of conformationally restricted quinolone antibacterial agents.

Cooper CS, Tufano MD, Donner PK, Chu DT. Cooper CS, et al. Among authors: tufano md. Bioorg Med Chem. 1996 Aug;4(8):1307-15. doi: 10.1016/0968-0896(96)00106-x. Bioorg Med Chem. 1996. PMID: 8879552

6

Novel hepatitis C virus replicon inhibitors: synthesis and structure-activity relationships of fused pyrimidine derivatives.

Krueger AC, Madigan DL, Beno DW, Betebenner DA, Carrick R, Green BE, He W, Liu D, Maring CJ, McDaniel KF, Mo H, Molla A, Motter CE, Pilot-Matias TJ, Tufano MD, Kempf DJ. Krueger AC, et al. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2212-5. doi: 10.1016/j.bmcl.2012.01.096. Epub 2012 Feb 2. Bioorg Med Chem Lett. 2012. PMID: 22342631

7

Novel inhibitors of Erm methyltransferases from NMR and parallel synthesis.

Hajduk PJ, Dinges J, Schkeryantz JM, Janowick D, Kaminski M, Tufano M, Augeri DJ, Petros A, Nienaber V, Zhong P, Hammond R, Coen M, Beutel B, Katz L, Fesik SW. Hajduk PJ, et al. Among authors: tufano m. J Med Chem. 1999 Sep 23;42(19):3852-9. doi: 10.1021/jm990293a. J Med Chem. 1999. PMID: 10508434

8

Double bond isosteres of the peptide bond: synthesis and biological activity of cholecystokinin (CCK) C-terminal hexapeptide analogs.

Shue YK, Tufano MD, Carrera GM Jr, Kopecka H, Kuyper SL, Holladay MW, Lin CW, Witte DG, Miller TR, Stashko M, et al. Shue YK, et al. Among authors: tufano md. Bioorg Med Chem. 1993 Sep;1(3):161-71. doi: 10.1016/s0968-0896(00)82117-3. Bioorg Med Chem. 1993. PMID: 8081848

9

Novel Asp32-replacement tetrapeptide analogues as potent and selective CCK-A agonists.

Elliott RL, Kopecka H, Tufano MD, Shue YK, Gauri AJ, Lin CW, Bianchi BR, Miller TR, Witte DG, Stashko MA, et al. Elliott RL, et al. Among authors: tufano md. J Med Chem. 1994 May 27;37(11):1562-8. doi: 10.1021/jm00037a005. J Med Chem. 1994. PMID: 8201590

10

Synthesis and biological activity of CCK heptapeptide analogues. Effects of conformational constraints and standard modifications on receptor subtype selectivity, functional activity in vitro, and appetite suppression in vivo.

Holladay MW, Bennett MJ, Tufano MD, Lin CW, Asin KE, Witte DG, Miller TR, Bianchi BR, Nikkel AL, Bednarz L, et al. Holladay MW, et al. Among authors: tufano md. J Med Chem. 1992 Aug 7;35(16):2919-28. doi: 10.1021/jm00094a001. J Med Chem. 1992. PMID: 1501220

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