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Targeting p38-MAPK in the ischaemic heart: kill or cure?
Bassi R, Heads R, Marber MS, Clark JE. Bassi R, et al. Curr Opin Pharmacol. 2008 Apr;8(2):141-6. doi: 10.1016/j.coph.2008.01.002. Epub 2008 Mar 4. Curr Opin Pharmacol. 2008. PMID: 18289939 Review.
The TAB1-p38α complex aggravates myocardial injury and can be targeted by small molecules.
De Nicola GF, Bassi R, Nichols C, Fernandez-Caggiano M, Golforoush PA, Thapa D, Anderson R, Martin ED, Verma S, Kleinjung J, Laing A, Hutchinson JP, Eaton P, Clark J, Marber MS. De Nicola GF, et al. Among authors: bassi r. JCI Insight. 2018 Aug 23;3(16):e121144. doi: 10.1172/jci.insight.121144. eCollection 2018 Aug 23. JCI Insight. 2018. PMID: 30135318 Free PMC article.
Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemia.
Tanno M, Bassi R, Gorog DA, Saurin AT, Jiang J, Heads RJ, Martin JL, Davis RJ, Flavell RA, Marber MS. Tanno M, et al. Among authors: bassi r. Circ Res. 2003 Aug 8;93(3):254-61. doi: 10.1161/01.RES.0000083490.43943.85. Epub 2003 Jun 26. Circ Res. 2003. PMID: 12829618
488 results