Huusfeldt PO - Search Results

1

Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration.

Knudsen LB, Nielsen PF, Huusfeldt PO, Johansen NL, Madsen K, Pedersen FZ, Thøgersen H, Wilken M, Agersø H. Knudsen LB, et al. Among authors: huusfeldt po. J Med Chem. 2000 May 4;43(9):1664-9. doi: 10.1021/jm9909645. J Med Chem. 2000. PMID: 10794683

2

Synthesis of novel GABA uptake inhibitors. 4. Bioisosteric transformation and successive optimization of known GABA uptake inhibitors leading to a series of potent anticonvulsant drug candidates.

Andersen KE, Sørensen JL, Huusfeldt PO, Knutsen LJ, Lau J, Lundt BF, Petersen H, Suzdak PD, Swedberg MD. Andersen KE, et al. Among authors: huusfeldt po. J Med Chem. 1999 Oct 21;42(21):4281-91. doi: 10.1021/jm980492e. J Med Chem. 1999. PMID: 10543872

3

Synthesis of novel GABA uptake inhibitors. Part 6: preparation and evaluation of N-Omega asymmetrically substituted nipecotic acid derivatives.

Andersen KE, Lau J, Lundt BF, Petersen H, Huusfeldt PO, Suzdak PD, Swedberg MD. Andersen KE, et al. Among authors: huusfeldt po. Bioorg Med Chem. 2001 Nov;9(11):2773-85. doi: 10.1016/s0968-0896(01)00148-1. Bioorg Med Chem. 2001. PMID: 11597457

4

Synthesis of novel gamma-aminobutyric acid (GABA) uptake inhibitors. 5.(1) Preparation and structure-activity studies of tricyclic analogues of known GABA uptake inhibitors.

Andersen KE, Sørensen JL, Lau J, Lundt BF, Petersen H, Huusfeldt PO, Suzdak PD, Swedberg MD. Andersen KE, et al. Among authors: huusfeldt po. J Med Chem. 2001 Jun 21;44(13):2152-63. doi: 10.1021/jm990513k. J Med Chem. 2001. PMID: 11405652

5

N-Alkoxypyrazoles as biomimetics for the alkoxyphenyl group in tamoxifen.

Wenckens M, Jakobsen P, Vedsø P, Huusfeldt PO, Gissel B, Barfoed M, Lundin Brockdorff B, Lykkesfeldt AE, Begtrup M. Wenckens M, et al. Among authors: huusfeldt po. Bioorg Med Chem. 2003 Apr 17;11(8):1883-99. doi: 10.1016/s0968-0896(02)00566-7. Bioorg Med Chem. 2003. PMID: 12659775

6

First nucleophilic aromatic substitution of annelated pyrazole.

Pawlas J, Vedsø P, Jakobsen P, Huusfeldt PO, Begtrup M. Pawlas J, et al. Among authors: huusfeldt po. J Org Chem. 2002 Jan 25;67(2):585-6. doi: 10.1021/jo010395k. J Org Chem. 2002. PMID: 11798334

7

Synthesis of 1-hydroxy-substituted pyrazolo[3,4-c]- and pyrazolo[4, 3-c]quinolines and -isoquinolines from 4- and 5-aryl-substituted 1-benzyloxypyrazoles.

Pawlas J, Vedsø P, Jakobsen P, Huusfeldt PO, Begtrup M. Pawlas J, et al. Among authors: huusfeldt po. J Org Chem. 2000 Dec 29;65(26):9001-6. doi: 10.1021/jo000986v. J Org Chem. 2000. PMID: 11149843

8

Novel anionic annelation tactics for construction of fused heteroaromatic frameworks. 1. Synthesis of 4-substituted pyrazolo[3,4-c]quinolines, 9-substituted pyrazolo[3,4-c]quinolines, and 1,4-dihydrochromeno[4,3-c]pyrazoles.

Pawlas J, Vedsø P, Jakobsen P, Huusfeldt PO, Begtrup M. Pawlas J, et al. Among authors: huusfeldt po. J Org Chem. 2001 Jun 15;66(12):4214-9. doi: 10.1021/jo001422u. J Org Chem. 2001. PMID: 11397156

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