Manoharan M - Search Results

1

Investigation of the proposed interdomain ribose zipper in hairpin ribozyme cleavage using 2'-modified nucleosides.

Earnshaw DJ, Hamm ML, Piccirilli JA, Karpeisky A, Beigelman L, Ross BS, Manoharan M, Gait MJ. Earnshaw DJ, et al. Among authors: manoharan m. Biochemistry. 2000 May 30;39(21):6410-21. doi: 10.1021/bi992974d. Biochemistry. 2000. PMID: 10828955

2

Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications.

Egli M, Minasov G, Tereshko V, Pallan PS, Teplova M, Inamati GB, Lesnik EA, Owens SR, Ross BS, Prakash TP, Manoharan M. Egli M, et al. Among authors: manoharan m. Biochemistry. 2005 Jun 28;44(25):9045-57. doi: 10.1021/bi050574m. Biochemistry. 2005. PMID: 15966728 Free article.

3

Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides.

An H, Wang T, Maier MA, Manoharan M, Ross BS, Cook PD. An H, et al. Among authors: manoharan m. J Org Chem. 2001 Apr 20;66(8):2789-801. doi: 10.1021/jo001699u. J Org Chem. 2001. PMID: 11304203

4

A Chemical Approach to Introduce 2,6-Diaminopurine and 2-Aminoadenine Conjugates into Oligonucleotides without Need for Protecting Groups.

Madaoui M, Datta D, Wassarman K, Zlatev I, Egli M, Ross BS, Manoharan M. Madaoui M, et al. Among authors: manoharan m. Org Lett. 2022 Aug 26;24(33):6111-6116. doi: 10.1021/acs.orglett.2c01848. Epub 2022 Aug 16. Org Lett. 2022. PMID: 35973215 Free PMC article.

5

Comparing in vitro and in vivo activity of 2'-O-[2-(methylamino)-2-oxoethyl]- and 2'-O-methoxyethyl-modified antisense oligonucleotides.

Prakash TP, Kawasaki AM, Wancewicz EV, Shen L, Monia BP, Ross BS, Bhat B, Manoharan M. Prakash TP, et al. Among authors: manoharan m. J Med Chem. 2008 May 8;51(9):2766-76. doi: 10.1021/jm701537z. Epub 2008 Apr 10. J Med Chem. 2008. PMID: 18399648

6

A 2'-O-thiol tether in the ribose moiety of nucleic acids for conjugation chemistry.

Manoharan M, Tivel KL, Ross B, Cook PD. Manoharan M, et al. Gene. 1994 Nov 4;149(1):147-56. doi: 10.1016/0378-1119(94)90423-5. Gene. 1994. PMID: 7958979

7

2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.

Li F, Sarkhel S, Wilds CJ, Wawrzak Z, Prakash TP, Manoharan M, Egli M. Li F, et al. Among authors: manoharan m. Biochemistry. 2006 Apr 4;45(13):4141-52. doi: 10.1021/bi052322r. Biochemistry. 2006. PMID: 16566588 Free PMC article.

8

2'-O-[2-(methylthio)ethyl]-modified oligonucleotide: an analogue of 2'-O-[2-(methoxy)-ethyl]-modified oligonucleotide with improved protein binding properties and high binding affinity to target RNA.

Prakash TP, Manoharan M, Kawasaki AM, Fraser AS, Lesnik EA, Sioufi N, Leeds JM, Teplova M, Egli M. Prakash TP, et al. Among authors: manoharan m. Biochemistry. 2002 Oct 1;41(39):11642-8. doi: 10.1021/bi020264t. Biochemistry. 2002. PMID: 12269806

9

An automated algorithm for sequence confirmation of chemically modified oligonucleotides by tandem mass spectrometry.

Kretschmer M, Lavine G, McArdle J, Kuchimanchi S, Murugaiah V, Manoharan M. Kretschmer M, et al. Among authors: manoharan m. Anal Biochem. 2010 Oct 15;405(2):213-23. doi: 10.1016/j.ab.2010.06.023. Epub 2010 Jun 17. Anal Biochem. 2010. PMID: 20599656

10

Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-alpha chain.

Karras JG, Maier MA, Lu T, Watt A, Manoharan M. Karras JG, et al. Among authors: manoharan m. Biochemistry. 2001 Jul 3;40(26):7853-9. doi: 10.1021/bi010263l. Biochemistry. 2001. PMID: 11425312

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

533 results

Search Page

Filters