Cheung A - Search Results

1

Brca1 required for T cell lineage development but not TCR loci rearrangement.

Mak TW, Hakem A, McPherson JP, Shehabeldin A, Zablocki E, Migon E, Duncan GS, Bouchard D, Wakeham A, Cheung A, Karaskova J, Sarosi I, Squire J, Marth J, Hakem R. Mak TW, et al. Among authors: cheung a. Nat Immunol. 2000 Jul;1(1):77-82. doi: 10.1038/76950. Nat Immunol. 2000. PMID: 10881179

2

Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis.

Cheung AM, Hande MP, Jalali F, Tsao MS, Skinnider B, Hirao A, McPherson JP, Karaskova J, Suzuki A, Wakeham A, You-Ten A, Elia A, Squire J, Bristow R, Hakem R, Mak TW. Cheung AM, et al. Cancer Res. 2002 Nov 1;62(21):6194-204. Cancer Res. 2002. PMID: 12414647

3

PTEN in the haematopoietic system and its therapeutic indications.

Cheung AM, Mak TW. Cheung AM, et al. Trends Mol Med. 2006 Nov;12(11):503-5. doi: 10.1016/j.molmed.2006.09.002. Epub 2006 Sep 25. Trends Mol Med. 2006. PMID: 16996801

4

Brca2 deficiency does not impair mammary epithelium development but promotes mammary adenocarcinoma formation in p53(+/-) mutant mice.

Cheung AM, Elia A, Tsao MS, Done S, Wagner KU, Hennighausen L, Hakem R, Mak TW. Cheung AM, et al. Cancer Res. 2004 Mar 15;64(6):1959-65. doi: 10.1158/0008-5472.can-03-2270. Cancer Res. 2004. PMID: 15026330

5

Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner.

Hirao A, Cheung A, Duncan G, Girard PM, Elia AJ, Wakeham A, Okada H, Sarkissian T, Wong JA, Sakai T, De Stanchina E, Bristow RG, Suda T, Lowe SW, Jeggo PA, Elledge SJ, Mak TW. Hirao A, et al. Among authors: cheung a. Mol Cell Biol. 2002 Sep;22(18):6521-32. doi: 10.1128/MCB.22.18.6521-6532.2002. Mol Cell Biol. 2002. PMID: 12192050 Free PMC article.

6

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo.

Sirard C, de la Pompa JL, Elia A, Itie A, Mirtsos C, Cheung A, Hahn S, Wakeham A, Schwartz L, Kern SE, Rossant J, Mak TW. Sirard C, et al. Among authors: cheung a. Genes Dev. 1998 Jan 1;12(1):107-19. doi: 10.1101/gad.12.1.107. Genes Dev. 1998. PMID: 9420335 Free PMC article.

7

Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response.

Jack MT, Woo RA, Hirao A, Cheung A, Mak TW, Lee PW. Jack MT, et al. Among authors: cheung a. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9825-9. doi: 10.1073/pnas.152053599. Epub 2002 Jul 3. Proc Natl Acad Sci U S A. 2002. PMID: 12097646 Free PMC article.

8

Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors.

Shaked Y, Ciarrocchi A, Franco M, Lee CR, Man S, Cheung AM, Hicklin DJ, Chaplin D, Foster FS, Benezra R, Kerbel RS. Shaked Y, et al. Among authors: cheung am. Science. 2006 Sep 22;313(5794):1785-7. doi: 10.1126/science.1127592. Science. 2006. PMID: 16990548

9

Detecting vascular changes in tumour xenografts using micro-ultrasound and micro-ct following treatment with VEGFR-2 blocking antibodies.

Cheung AM, Brown AS, Cucevic V, Roy M, Needles A, Yang V, Hicklin DJ, Kerbel RS, Foster FS. Cheung AM, et al. Ultrasound Med Biol. 2007 Aug;33(8):1259-68. doi: 10.1016/j.ultrasmedbio.2007.01.015. Epub 2007 Apr 30. Ultrasound Med Biol. 2007. PMID: 17467156

10

Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia.

Franco M, Man S, Chen L, Emmenegger U, Shaked Y, Cheung AM, Brown AS, Hicklin DJ, Foster FS, Kerbel RS. Franco M, et al. Cancer Res. 2006 Apr 1;66(7):3639-48. doi: 10.1158/0008-5472.CAN-05-3295. Cancer Res. 2006. PMID: 16585189

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