Jack C - Search Results

1

Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling.

Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Kimberly WT, Weinmaster G, Selkoe DJ, Hyman BT. Berezovska O, et al. Among authors: jack c. J Neurochem. 2000 Aug;75(2):583-93. doi: 10.1046/j.1471-4159.2000.0750583.x. J Neurochem. 2000. PMID: 10899933 Free article.

2

Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila.

Micchelli CA, Esler WP, Kimberly WT, Jack C, Berezovska O, Kornilova A, Hyman BT, Perrimon N, Wolfe MS. Micchelli CA, et al. Among authors: jack c. FASEB J. 2003 Jan;17(1):79-81. doi: 10.1096/fj.02-0394fje. Epub 2002 Nov 1. FASEB J. 2003. PMID: 12424225

3

Rapid Notch1 nuclear translocation after ligand binding depends on presenilin-associated gamma-secretase activity.

Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Weinmaster G, Selkoe DJ, Hyman BT. Berezovska O, et al. Among authors: jack c. Ann N Y Acad Sci. 2000;920:223-6. doi: 10.1111/j.1749-6632.2000.tb06926.x. Ann N Y Acad Sci. 2000. PMID: 11193154

4

Effect of PS1 deficiency and an APP gamma-secretase inhibitor on Notch1 signaling in primary mammalian neurons.

Jack C, Berezovska O, Wolfe MS, Hyman BT. Jack C, et al. Brain Res Mol Brain Res. 2001 Mar 5;87(2):166-74. doi: 10.1016/s0169-328x(01)00010-9. Brain Res Mol Brain Res. 2001. PMID: 11245918

5

Notch1 and amyloid precursor protein are competitive substrates for presenilin1-dependent gamma-secretase cleavage.

Berezovska O, Jack C, Deng A, Gastineau N, Rebeck GW, Hyman BT. Berezovska O, et al. Among authors: jack c. J Biol Chem. 2001 Aug 10;276(32):30018-23. doi: 10.1074/jbc.M008268200. Epub 2001 Jun 14. J Biol Chem. 2001. PMID: 11408475 Free article.

6

Quantitative Assessment of the Effect of Chronic Kidney Disease on Plasma P-Tau217 Concentrations.

Bornhorst JA, Lundgreen CS, Weigand SD, Figdore DJ, Wiste H, Griswold M, Vemuri P, Graff-Radford J, Knopman DS, Cogswell P, Jack CR, Petersen RC, Algeciras-Schimnich A. Bornhorst JA, et al. Among authors: jack cr. Neurology. 2025 Feb 11;104(3):e210287. doi: 10.1212/WNL.0000000000210287. Epub 2025 Jan 17. Neurology. 2025. PMID: 39823562

7

White matter hyperintensities and TDP-43 pathology in Alzheimer's disease.

Carlos AF, Weigand SD, Pham NTT, Petersen RC, Jack CR Jr, Dickson DW, Whitwell JL, Josephs KA. Carlos AF, et al. Among authors: jack cr jr. Alzheimers Dement. 2025 Jan 17:ealz14516. doi: 10.1002/alz.14516. Online ahead of print. Alzheimers Dement. 2025. PMID: 39821594

8

Association of plasma biomarkers of Alzheimer's pathology and neurodegeneration with gait performance in older adults.

Ali F, Syrjanen JA, Figdore DJ, Kremers WK, Mielke MM, Jack CR, Knopman DS, Vemuri P, Graff-Radford J, Windham BG, Barnard LR, Petersen RC, Algeciras-Schimnich A. Ali F, et al. Among authors: jack cr. Commun Med (Lond). 2025 Jan 16;5(1):19. doi: 10.1038/s43856-024-00713-6. Commun Med (Lond). 2025. PMID: 39820537 Free PMC article.

9

Brain mechanical properties predict longitudinal cognitive change in aging and Alzheimer's disease.

Pavuluri K, Huston J 3rd, Ehman RL, Manduca A, Vemuri P, Jack CR Jr, Senjem ML, Murphy MC. Pavuluri K, et al. Among authors: jack cr jr. Neurobiol Aging. 2025 Jan 9;147:203-212. doi: 10.1016/j.neurobiolaging.2025.01.001. Online ahead of print. Neurobiol Aging. 2025. PMID: 39813771 Free article.

10

Longitudinal FDG-PET Metabolic Change Along the Lewy Body Continuum.

Ferreira D, Przybelski SA, Lesnick TG, Diaz-Galvan P, Schwarz CG, Murray MM, Dickson DW, Nguyen A, Reichard RR, Senjem ML, Gunter JL, Jack CR Jr, Min PH, Jain MK, Miyagawa T, Forsberg LK, Fields JA, Savica R, Graff-Radford J, Ramanan VK, Jones DT, Botha H, St Louis EK, Knopman DS, Graff-Radford NR, Day GS, Ferman TJ, Kremers WK, Petersen RC, Boeve BF, Lowe VJ, Kantarci K. Ferreira D, et al. Among authors: jack cr jr. JAMA Neurol. 2025 Jan 13. doi: 10.1001/jamaneurol.2024.4643. Online ahead of print. JAMA Neurol. 2025. PMID: 39804619

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