Werth N - Search Results

1

Recent advances in the biochemistry of glycosphingolipid metabolism.

Kolter T, Doering T, Wilkening G, Werth N, Sandhoff K. Kolter T, et al. Among authors: werth n. Biochem Soc Trans. 1999 Aug;27(4):409-15. doi: 10.1042/bst0270409. Biochem Soc Trans. 1999. PMID: 10917612 Review. No abstract available.

2

The enzyme-binding region of human GM2-activator protein.

Wendeler M, Werth N, Maier T, Schwarzmann G, Kolter T, Schoeniger M, Hoffmann D, Lemm T, Saenger W, Sandhoff K. Wendeler M, et al. Among authors: werth n. FEBS J. 2006 Mar;273(5):982-91. doi: 10.1111/j.1742-4658.2006.05126.x. FEBS J. 2006. PMID: 16478472 Free article.

3

Degradation of membrane-bound ganglioside GM2 by beta -hexosaminidase A. Stimulation by GM2 activator protein and lysosomal lipids.

Werth N, Schuette CG, Wilkening G, Lemm T, Sandhoff K. Werth N, et al. J Biol Chem. 2001 Apr 20;276(16):12685-90. doi: 10.1074/jbc.M007970200. Epub 2001 Jan 16. J Biol Chem. 2001. PMID: 11278374 Free article.

4

Expression of the GM2-activator protein in the methylotrophic yeast Pichia pastoris, purification, isotopic labeling, and biophysical characterization.

Wendeler M, Hoernschemeyer J, John M, Werth N, Schoeniger M, Lemm T, Hartmann R, Kessler H, Sandhoff K. Wendeler M, et al. Among authors: werth n. Protein Expr Purif. 2004 Mar;34(1):147-57. doi: 10.1016/j.pep.2003.11.010. Protein Expr Purif. 2004. PMID: 14766311

5

Interactions of acid sphingomyelinase and lipid bilayers in the presence of the tricyclic antidepressant desipramine.

Kölzer M, Werth N, Sandhoff K. Kölzer M, et al. Among authors: werth n. FEBS Lett. 2004 Feb 13;559(1-3):96-8. doi: 10.1016/S0014-5793(04)00033-X. FEBS Lett. 2004. PMID: 14960314 Free article.

6

Phosphatidylinositol-3,5-Bisphosphate is a potent and selective inhibitor of acid sphingomyelinase.

Kölzer M, Arenz C, Ferlinz K, Werth N, Schulze H, Klingenstein R, Sandhoff K. Kölzer M, et al. Among authors: werth n. Biol Chem. 2003 Sep;384(9):1293-8. doi: 10.1515/BC.2003.144. Biol Chem. 2003. PMID: 14515991

7

Purified recombinant human prosaposin forms oligomers that bind procathepsin D and affect its autoactivation.

Gopalakrishnan MM, Grosch HW, Locatelli-Hoops S, Werth N, Smolenová E, Nettersheim M, Sandhoff K, Hasilik A. Gopalakrishnan MM, et al. Among authors: werth n. Biochem J. 2004 Nov 1;383(Pt. 3):507-15. doi: 10.1042/BJ20040175. Biochem J. 2004. PMID: 15255780 Free PMC article.

8

Conditional LoxP-flanked glucosylceramide synthase allele controlling glycosphingolipid synthesis.

Yamashita T, Allende ML, Kalkofen DN, Werth N, Sandhoff K, Proia RL. Yamashita T, et al. Among authors: werth n. Genesis. 2005 Dec;43(4):175-80. doi: 10.1002/gene.20167. Genesis. 2005. PMID: 16283624

9

Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures.

Kawai H, Allende ML, Wada R, Kono M, Sango K, Deng C, Miyakawa T, Crawley JN, Werth N, Bierfreund U, Sandhoff K, Proia RL. Kawai H, et al. Among authors: werth n. J Biol Chem. 2001 Mar 9;276(10):6885-8. doi: 10.1074/jbc.C000847200. Epub 2000 Dec 27. J Biol Chem. 2001. PMID: 11133999 Free article.

10

Systemic inflammation in glucocerebrosidase-deficient mice with minimal glucosylceramide storage.

Mizukami H, Mi Y, Wada R, Kono M, Yamashita T, Liu Y, Werth N, Sandhoff R, Sandhoff K, Proia RL. Mizukami H, et al. Among authors: werth n. J Clin Invest. 2002 May;109(9):1215-21. doi: 10.1172/JCI14530. J Clin Invest. 2002. PMID: 11994410 Free PMC article.

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