Chohan KK - Search Results

1

Differential coupling through Val-344 and Tyr-442 of trimethylamine dehydrogenase in electron transfer reactions with ferricenium ions and electron transferring flavoprotein.

Basran J, Chohan KK, Sutcliffe MJ, Scrutton NS. Basran J, et al. Among authors: chohan kk. Biochemistry. 2000 Aug 8;39(31):9188-200. doi: 10.1021/bi0006868. Biochemistry. 2000. PMID: 10924112

2

Flavin radicals, conformational sampling and robust design principles in interprotein electron transfer: the trimethylamine dehydrogenase-electron-transferring flavoprotein complex.

Leys D, Basran J, Talfournier F, Chohan KK, Munro AW, Sutcliffe MJ, Scrutton NS. Leys D, et al. Among authors: chohan kk. Biochem Soc Symp. 2004;(71):1-14. doi: 10.1042/bss0710001. Biochem Soc Symp. 2004. PMID: 15777008 Review.

3

Electron transfer in trimethylamine dehydrogenase and electron-transferring flavoprotein.

Scrutton NS, Basran J, Wilson EK, Chohan KK, Jang MH, Sutcliffe MJ, Hille R. Scrutton NS, et al. Among authors: chohan kk. Biochem Soc Trans. 1999 Feb;27(2):196-201. doi: 10.1042/bst0270196. Biochem Soc Trans. 1999. PMID: 10093733 Review. No abstract available.

4

Protein dynamics enhance electronic coupling in electron transfer complexes.

Chohan KK, Jones M, Grossmann JG, Frerman FE, Scrutton NS, Sutcliffe MJ. Chohan KK, et al. J Biol Chem. 2001 Sep 7;276(36):34142-7. doi: 10.1074/jbc.M101341200. Epub 2001 Jun 27. J Biol Chem. 2001. PMID: 11429403 Free article.

5

Structure of the complex of Cdc42Hs with a peptide derived from P-21 activated kinase.

Gizachew D, Guo W, Chohan KK, Sutcliffe MJ, Oswald RE. Gizachew D, et al. Among authors: chohan kk. Biochemistry. 2000 Apr 11;39(14):3963-71. doi: 10.1021/bi992646d. Biochemistry. 2000. PMID: 10747784

6

QM/MM studies show substantial tunneling for the hydrogen-transfer reaction in methylamine dehydrogenase.

Faulder PF, Tresadern G, Chohan KK, Scrutton NS, Sutcliffe MJ, Hillier IH, Burton NA. Faulder PF, et al. Among authors: chohan kk. J Am Chem Soc. 2001 Sep 5;123(35):8604-5. doi: 10.1021/ja016219a. J Am Chem Soc. 2001. PMID: 11525672 No abstract available.

7

Cysteine mutagenesis and homology modeling of the ligand-binding site of a kainate-binding protein.

Wo ZG, Chohan KK, Chen H, Sutcliffe MJ, Oswald RE. Wo ZG, et al. Among authors: chohan kk. J Biol Chem. 1999 Dec 24;274(52):37210-8. doi: 10.1074/jbc.274.52.37210. J Biol Chem. 1999. PMID: 10601284 Free article.

8

Synthesis and biological evaluation of N-alkylated 8-oxybenz[c]azepine derivatives as selective PPARδ agonists.

Luckhurst CA, Ratcliffe M, Stein L, Furber M, Botterell S, Laughton D, Tomlinson W, Weaver R, Chohan K, Walding A. Luckhurst CA, et al. Bioorg Med Chem Lett. 2011 Jan 1;21(1):531-6. doi: 10.1016/j.bmcl.2010.10.083. Epub 2010 Oct 23. Bioorg Med Chem Lett. 2011. PMID: 21075629

9

Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules.

Luker T, Alcaraz L, Chohan KK, Blomberg N, Brown DS, Butlin RJ, Elebring T, Griffin AM, Guile S, St-Gallay S, Swahn BM, Swallow S, Waring MJ, Wenlock MC, Leeson PD. Luker T, et al. Among authors: chohan kk. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5673-9. doi: 10.1016/j.bmcl.2011.07.074. Epub 2011 Jul 27. Bioorg Med Chem Lett. 2011. PMID: 21852131

10

A rapid computational filter for cytochrome P450 1A2 inhibition potential of compound libraries.

Chohan KK, Paine SW, Mistry J, Barton P, Davis AM. Chohan KK, et al. J Med Chem. 2005 Aug 11;48(16):5154-61. doi: 10.1021/jm048959a. J Med Chem. 2005. PMID: 16078835

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