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Page 1
A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.
Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson JA, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel KP, Voegeling S, Guenet JL, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher EM, Martin J, Rastan S, Brown SD, Hunter J. Nolan PM, et al. Among authors: arkell r. Nat Genet. 2000 Aug;25(4):440-3. doi: 10.1038/78140. Nat Genet. 2000. PMID: 10932191
New semidominant mutations that affect mouse development.
Bogani D, Warr N, Elms P, Davies J, Tymowska-Lalanne Z, Goldsworthy M, Cox RD, Keays DA, Flint J, Wilson V, Nolan P, Arkell R. Bogani D, et al. Among authors: arkell r. Genesis. 2004 Oct;40(2):109-117. doi: 10.1002/gene.20071. Genesis. 2004. PMID: 15384171
Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development.
Grimmond S, Van Hateren N, Siggers P, Arkell R, Larder R, Soares MB, de Fatima Bonaldo M, Smith L, Tymowska-Lalanne Z, Wells C, Greenfield A. Grimmond S, et al. Among authors: arkell r. Hum Mol Genet. 2000 Jun 12;9(10):1553-60. doi: 10.1093/hmg/9.10.1553. Hum Mol Genet. 2000. PMID: 10888606
Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen.
Bogani D, Willoughby C, Davies J, Kaur K, Mirza G, Paudyal A, Haines H, McKeone R, Cadman M, Pieles G, Schneider JE, Bhattacharya S, Hardy A, Nolan PM, Tripodis N, Depew MJ, Chandrasekara R, Duncan G, Sharpe PT, Greenfield A, Denny P, Brown SD, Ragoussis J, Arkell RM. Bogani D, et al. Among authors: arkell rm. Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12477-82. doi: 10.1073/pnas.0500584102. Epub 2005 Aug 18. Proc Natl Acad Sci U S A. 2005. PMID: 16109771 Free PMC article.
Organization and evolution of a gene-rich region of the mouse genome: a 12.7-Mb region deleted in the Del(13)Svea36H mouse.
Mallon AM, Wilming L, Weekes J, Gilbert JG, Ashurst J, Peyrefitte S, Matthews L, Cadman M, McKeone R, Sellick CA, Arkell R, Botcherby MR, Strivens MA, Campbell RD, Gregory S, Denny P, Hancock JM, Rogers J, Brown SD. Mallon AM, et al. Among authors: arkell r. Genome Res. 2004 Oct;14(10A):1888-901. doi: 10.1101/gr.2478604. Epub 2004 Sep 13. Genome Res. 2004. PMID: 15364904 Free PMC article.
Upregulation of PKD1L2 provokes a complex neuromuscular disease in the mouse.
Mackenzie FE, Romero R, Williams D, Gillingwater T, Hilton H, Dick J, Riddoch-Contreras J, Wong F, Ireson L, Powles-Glover N, Riley G, Underhill P, Hough T, Arkell R, Greensmith L, Ribchester RR, Blanco G. Mackenzie FE, et al. Among authors: arkell r. Hum Mol Genet. 2009 Oct 1;18(19):3553-66. doi: 10.1093/hmg/ddp304. Epub 2009 Jul 4. Hum Mol Genet. 2009. PMID: 19578180 Free PMC article.
80 results