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Constitutive tyrosine phosphorylation of ErbB-2 via Jak2 by autocrine secretion of prolactin in human breast cancer.
Yamauchi T, Yamauchi N, Ueki K, Sugiyama T, Waki H, Miki H, Tobe K, Matsuda S, Tsushima T, Yamamoto T, Fujita T, Taketani Y, Fukayama M, Kimura S, Yazaki Y, Nagai R, Kadowaki T. Yamauchi T, et al. Among authors: kadowaki t. J Biol Chem. 2000 Oct 27;275(43):33937-44. doi: 10.1074/jbc.M000743200. J Biol Chem. 2000. PMID: 10938266 Free article.
Identification of a 190-kDa protein as a novel substrate for the insulin receptor kinase functionally similar to insulin receptor substrate-1.
Tobe K, Tamemoto H, Yamauchi T, Aizawa S, Yazaki Y, Kadowaki T. Tobe K, et al. Among authors: kadowaki t. J Biol Chem. 1995 Mar 17;270(11):5698-701. doi: 10.1074/jbc.270.11.5698. J Biol Chem. 1995. PMID: 7534300 Free article.
Recently, we generated mice with a targeted disruption of the insulin receptor substrate-1 (IRS-1) gene and demonstrated that they exhibited growth retardation and mild insulin resistance, suggesting the presence of IRS-1-independent pathway that partially substitutes for IRS-1 i …
Recently, we generated mice with a targeted disruption of the insulin receptor substrate-1 (IRS-1) gene and demonstrated that they exhibited …
Mutant of insulin receptor substrate-1 incapable of activating phosphatidylinositol 3-kinase did not mediate insulin-stimulated maturation of Xenopus laevis oocytes.
Yamamoto-Honda R, Honda Z, Ueki K, Tobe K, Kaburagi Y, Takahashi Y, Tamemoto H, Suzuki T, Itoh K, Akanuma Y, Yazaki Y, Kadowaki T. Yamamoto-Honda R, et al. Among authors: kadowaki t. J Biol Chem. 1996 Nov 8;271(45):28677-81. doi: 10.1074/jbc.271.45.28677. J Biol Chem. 1996. PMID: 8910502 Free article.
Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase.
Yamauchi T, Kaburagi Y, Ueki K, Tsuji Y, Stark GR, Kerr IM, Tsushima T, Akanuma Y, Komuro I, Tobe K, Yazaki Y, Kadowaki T. Yamauchi T, et al. Among authors: kadowaki t. J Biol Chem. 1998 Jun 19;273(25):15719-26. doi: 10.1074/jbc.273.25.15719. J Biol Chem. 1998. PMID: 9624169 Free article.
Growth hormone-induced tyrosine phosphorylation of EGF receptor as an essential element leading to MAP kinase activation and gene expression.
Yamauchi T, Ueki K, Tobe K, Tamemoto H, Sekine N, Wada M, Honjo M, Takahashi M, Takahashi T, Hirai H, Tsushima T, Akanuma Y, Fujita T, Komuro I, Yazaki Y, Kadowaki T. Yamauchi T, et al. Among authors: kadowaki t. Endocr J. 1998 Apr;45 Suppl:S27-31. doi: 10.1507/endocrj.45.suppl_s27. Endocr J. 1998. PMID: 9790226 Free article. Review.
1,596 results