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Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease.
Shen Y, Muramatsu SI, Ikeguchi K, Fujimoto KI, Fan DS, Ogawa M, Mizukami H, Urabe M, Kume A, Nagatsu I, Urano F, Suzuki T, Ichinose H, Nagatsu T, Monahan J, Nakano I, Ozawa K. Shen Y, et al. Among authors: ikeguchi k. Hum Gene Ther. 2000 Jul 20;11(11):1509-19. doi: 10.1089/10430340050083243. Hum Gene Ther. 2000. PMID: 10945765
Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes.
Muramatsu S, Fujimoto K, Ikeguchi K, Shizuma N, Kawasaki K, Ono F, Shen Y, Wang L, Mizukami H, Kume A, Matsumura M, Nagatsu I, Urano F, Ichinose H, Nagatsu T, Terao K, Nakano I, Ozawa K. Muramatsu S, et al. Among authors: ikeguchi k. Hum Gene Ther. 2002 Feb 10;13(3):345-54. doi: 10.1089/10430340252792486. Hum Gene Ther. 2002. PMID: 11860702
Adeno-associated viral vectors for Parkinson's disease.
Muramatsu S, Wang L, Ikeguchi K, Fujimoto K, Nakano I, Okada T, Mizukami H, Hanazono Y, Kume A, Nakano I, Ozawa K. Muramatsu S, et al. Among authors: ikeguchi k. Int Rev Neurobiol. 2003;55:205-22. doi: 10.1016/s0074-7742(03)01009-2. Int Rev Neurobiol. 2003. PMID: 12968538 Review. No abstract available.
Behavioral recovery in 6-hydroxydopamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectors.
Fan DS, Ogawa M, Fujimoto KI, Ikeguchi K, Ogasawara Y, Urabe M, Nishizawa M, Nakano I, Yoshida M, Nagatsu I, Ichinose H, Nagatsu T, Kurtzman GJ, Ozawa K. Fan DS, et al. Among authors: ikeguchi k. Hum Gene Ther. 1998 Nov 20;9(17):2527-35. doi: 10.1089/hum.1998.9.17-2527. Hum Gene Ther. 1998. PMID: 9853519
44 results