Frittitta L - Search Results

1

Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis.

Gu HF, Almgren P, Lindholm E, Frittitta L, Pizzuti A, Trischitta V, Groop LC. Gu HF, et al. Among authors: frittitta l. Diabetes. 2000 Sep;49(9):1601-3. doi: 10.2337/diabetes.49.9.1601. Diabetes. 2000. PMID: 10969847

2

A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance.

Pizzuti A, Frittitta L, Argiolas A, Baratta R, Goldfine ID, Bozzali M, Ercolino T, Scarlato G, Iacoviello L, Vigneri R, Tassi V, Trischitta V. Pizzuti A, et al. Among authors: frittitta l. Diabetes. 1999 Sep;48(9):1881-4. doi: 10.2337/diabetes.48.9.1881. Diabetes. 1999. PMID: 10480624 Clinical Trial.

3

A PC-1 amino acid variant (K121Q) is associated with faster progression of renal disease in patients with type 1 diabetes and albuminuria.

De Cosmo S, Argiolas A, Miscio G, Thomas S, Piras GP, Trevisan R, Perin PC, Bacci S, Zucaro L, Margaglione M, Frittitta L, Pizzuti A, Tassi V, Viberti GC, Trischitta V. De Cosmo S, et al. Among authors: frittitta l. Diabetes. 2000 Mar;49(3):521-4. doi: 10.2337/diabetes.49.3.521. Diabetes. 2000. PMID: 10868979

4

The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.

Rasmussen SK, Urhammer SA, Pizzuti A, Echwald SM, Ekstrøm CT, Hansen L, Hansen T, Borch-Johnsen K, Frittitta L, Trischitta V, Pedersen O. Rasmussen SK, et al. Among authors: frittitta l. Diabetes. 2000 Sep;49(9):1608-11. doi: 10.2337/diabetes.49.9.1608. Diabetes. 2000. PMID: 10969849

5

The Q allele variant (GLN121) of membrane glycoprotein PC-1 interacts with the insulin receptor and inhibits insulin signaling more effectively than the common K allele variant (LYS121).

Costanzo BV, Trischitta V, Di Paola R, Spampinato D, Pizzuti A, Vigneri R, Frittitta L. Costanzo BV, et al. Among authors: frittitta l. Diabetes. 2001 Apr;50(4):831-6. doi: 10.2337/diabetes.50.4.831. Diabetes. 2001. PMID: 11289049

6

A cluster of three single nucleotide polymorphisms in the 3'-untranslated region of human glycoprotein PC-1 gene stabilizes PC-1 mRNA and is associated with increased PC-1 protein content and insulin resistance-related abnormalities.

Frittitta L, Ercolino T, Bozzali M, Argiolas A, Graci S, Santagati MG, Spampinato D, Di Paola R, Cisternino C, Tassi V, Vigneri R, Pizzuti A, Trischitta V. Frittitta L, et al. Diabetes. 2001 Aug;50(8):1952-5. doi: 10.2337/diabetes.50.8.1952. Diabetes. 2001. PMID: 11473061

7

Role of the ENPP1 K121Q polymorphism in glucose homeostasis.

Baratta R, Rossetti P, Prudente S, Barbetti F, Sudano D, Nigro A, Farina MG, Pellegrini F, Trischitta V, Frittitta L. Baratta R, et al. Among authors: frittitta l. Diabetes. 2008 Dec;57(12):3360-4. doi: 10.2337/db07-1830. Epub 2008 Sep 5. Diabetes. 2008. PMID: 18776139 Free PMC article.

8

Early molecular defects in human insulin resistance: studies in healthy subjects with low insulin sensitivity.

Trischitta V, Frittitta L, Vigneri R. Trischitta V, et al. Among authors: frittitta l. Diabetes Metab Rev. 1997 Sep;13(3):147-62. doi: 10.1002/(sici)1099-0895(199709)13:3<147::aid-dmr180>3.0.co;2-f. Diabetes Metab Rev. 1997. PMID: 9307888 Review. No abstract available.

9

Membrane glycoprotein PC-1 and insulin resistance.

Goldfine ID, Maddux BA, Youngren JF, Frittitta L, Trischitta V, Dohm GL. Goldfine ID, et al. Among authors: frittitta l. Mol Cell Biochem. 1998 May;182(1-2):177-84. Mol Cell Biochem. 1998. PMID: 9609127 Review.

10

Elevated PC-1 content in cultured skin fibroblasts correlates with decreased in vivo and in vitro insulin action in nondiabetic subjects: evidence that PC-1 may be an intrinsic factor in impaired insulin receptor signaling.

Frittitta L, Spampinato D, Solini A, Nosadini R, Goldfine ID, Vigneri R, Trischitta V. Frittitta L, et al. Diabetes. 1998 Jul;47(7):1095-100. doi: 10.2337/diabetes.47.7.1095. Diabetes. 1998. PMID: 9648833

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