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838 results

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Page 1
The discovery of non-basic atrial natriuretic peptide clearance receptor antagonists. Part 1.
Veale CA, Alford VC, Aharony D, Banville DL, Bialecki RA, Brown FJ, Damewood JR Jr, Dantzman CL, Edwards PD, Jacobs RT, Mauger RC, Murphy MM, Palmer W, Pine KK, Rumsey WL, Garcia-Davenport LE, Shaw A, Steelman GB, Surian JM, Vacek EP. Veale CA, et al. Among authors: palmer w. Bioorg Med Chem Lett. 2000 Sep 4;10(17):1949-52. doi: 10.1016/s0960-894x(00)00387-5. Bioorg Med Chem Lett. 2000. PMID: 10987424
Design, synthesis, and SAR of tachykinin antagonists: modulation of balance in NK(1)/NK(2) receptor antagonist activity.
Albert JS, Aharony D, Andisik D, Barthlow H, Bernstein PR, Bialecki RA, Dedinas R, Dembofsky BT, Hill D, Kirkland K, Koether GM, Kosmider BJ, Ohnmacht C, Palmer W, Potts W, Rumsey W, Shen L, Shenvi A, Sherwood S, Warwick PJ, Russell K. Albert JS, et al. Among authors: palmer w. J Med Chem. 2002 Aug 29;45(18):3972-83. doi: 10.1021/jm020094i. J Med Chem. 2002. PMID: 12190319
4-Piperidin-4-ylidenemethyl-benzamides as δ-opioid receptor agonists for CNS indications: identifying clinical candidates.
Dantzman CL, King MM, Ernst GE, Wang X, McCauley JP Jr, Andisik DW, Brush K, Bui KH, Frietze W, Hoesch V, Liu J, Palmer WE, Spear N, Hudzik TJ, Wesolowski SS. Dantzman CL, et al. Among authors: palmer we. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1174-8. doi: 10.1016/j.bmcl.2011.11.089. Epub 2011 Nov 30. Bioorg Med Chem Lett. 2012. PMID: 22197137
Multiparameter exploration of piperazine derivatives as δ-opioid receptor agonists for CNS indications.
McCauley JP Jr, Dantzman CL, King MM, Ernst GE, Wang X, Brush K, Palmer WE, Frietze W, Andisik DW, Hoesch V, Doring K, Hulsizer J, Bui KH, Liu J, Hudzik TJ, Wesolowski SS. McCauley JP Jr, et al. Among authors: palmer we. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1169-73. doi: 10.1016/j.bmcl.2011.11.088. Epub 2011 Dec 7. Bioorg Med Chem Lett. 2012. PMID: 22197139
Bicyclo((aryl)methyl)benzamides as inhibitors of GlyT1.
Varnes JG, Xiong H, Forst JM, Holmquist CR, Ernst GE, Frietze W, Dembofsky B, Andisik DW, Palmer WE, Hinkley L, Steelman GB, Wilkins DE, Tian G, Jonak G, Potts WM, Wang X, Brugel TA, Alhambra C, Wood MW, Veale CA, Albert JS. Varnes JG, et al. Among authors: palmer we. Bioorg Med Chem Lett. 2018 Apr 1;28(6):1043-1049. doi: 10.1016/j.bmcl.2018.02.029. Epub 2018 Feb 14. Bioorg Med Chem Lett. 2018. PMID: 29486970
Author Correction: A deep catalogue of protein-coding variation in 983,578 individuals.
Sun KY, Bai X, Chen S, Bao S, Zhang C, Kapoor M, Backman J, Joseph T, Maxwell E, Mitra G, Gorovits A, Mansfield A, Boutkov B, Gokhale S, Habegger L, Marcketta A, Locke AE, Ganel L, Hawes A, Kessler MD, Sharma D, Staples J, Bovijn J, Gelfman S, Di Gioia A, Rajagopal VM, Lopez A, Varela JR, Alegre-Díaz J, Berumen J, Tapia-Conyer R, Kuri-Morales P, Torres J, Emberson J, Collins R; Regeneron Genetics Center; RGC-ME Cohort Partners; Cantor M, Thornton T, Kang HM, Overton JD, Shuldiner AR, Cremona ML, Nafde M, Baras A, Abecasis G, Marchini J, Reid JG, Salerno W, Balasubramanian S. Sun KY, et al. Nature. 2025 Jan;637(8047):E26. doi: 10.1038/s41586-024-08571-x. Nature. 2025. PMID: 39779867 Free PMC article. No abstract available.
838 results