Lu Y - Search Results

1

Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein.

Brimer C, Dalton JT, Zhu Z, Schuetz J, Yasuda K, Vanin E, Relling MV, Lu Y, Schuetz EG. Brimer C, et al. Among authors: lu y. Pharm Res. 2000 Jul;17(7):803-10. doi: 10.1023/a:1007599923694. Pharm Res. 2000. PMID: 10990198

2

Novel tubulin polymerization inhibitors overcome multidrug resistance and reduce melanoma lung metastasis.

Wang Z, Chen J, Wang J, Ahn S, Li CM, Lu Y, Loveless VS, Dalton JT, Miller DD, Li W. Wang Z, et al. Among authors: lu y. Pharm Res. 2012 Nov;29(11):3040-52. doi: 10.1007/s11095-012-0726-4. Epub 2012 Mar 13. Pharm Res. 2012. PMID: 22410804 Free PMC article.

3

Orally bioavailable tubulin antagonists for paclitaxel-refractory cancer.

Li CM, Lu Y, Chen J, Costello TA, Narayanan R, Dalton MN, Snyder LM, Ahn S, Li W, Miller DD, Dalton JT. Li CM, et al. Among authors: lu y. Pharm Res. 2012 Nov;29(11):3053-63. doi: 10.1007/s11095-012-0814-5. Epub 2012 Jul 4. Pharm Res. 2012. PMID: 22760659 Free PMC article.

4

Discovery of novel 2-aryl-4-benzoyl-imidazole (ABI-III) analogues targeting tubulin polymerization as antiproliferative agents.

Chen J, Ahn S, Wang J, Lu Y, Dalton JT, Miller DD, Li W. Chen J, et al. Among authors: lu y. J Med Chem. 2012 Aug 23;55(16):7285-9. doi: 10.1021/jm300564b. Epub 2012 Aug 6. J Med Chem. 2012. PMID: 22783954 Free PMC article.

5

Design, synthesis, and SAR studies of 4-substituted methoxylbenzoyl-aryl-thiazoles analogues as potent and orally bioavailable anticancer agents.

Lu Y, Li CM, Wang Z, Chen J, Mohler ML, Li W, Dalton JT, Miller DD. Lu Y, et al. J Med Chem. 2011 Jul 14;54(13):4678-93. doi: 10.1021/jm2003427. Epub 2011 Jun 7. J Med Chem. 2011. PMID: 21557538 Free PMC article.

6

Synthesis and antiproliferative activity of thiazolidine analogs for melanoma.

Li W, Lu Y, Wang Z, Dalton JT, Miller DD. Li W, et al. Among authors: lu y. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4113-7. doi: 10.1016/j.bmcl.2007.05.059. Epub 2007 May 23. Bioorg Med Chem Lett. 2007. PMID: 17561392

7

Drug metabolism and pharmacokinetics of 4-substituted methoxybenzoyl-aryl-thiazoles.

Li CM, Lu Y, Narayanan R, Miller DD, Dalton JT. Li CM, et al. Among authors: lu y. Drug Metab Dispos. 2010 Nov;38(11):2032-9. doi: 10.1124/dmd.110.034348. Epub 2010 Jul 30. Drug Metab Dispos. 2010. PMID: 20675405

8

Synthesis and antiproliferative activity of imidazole and imidazoline analogs for melanoma.

Chen J, Wang Z, Lu Y, Dalton JT, Miller DD, Li W. Chen J, et al. Among authors: lu y. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3183-7. doi: 10.1016/j.bmcl.2008.04.073. Epub 2008 May 1. Bioorg Med Chem Lett. 2008. PMID: 18477505 Free PMC article.

9

Synthesis, in vitro structure-activity relationship, and in vivo studies of 2-arylthiazolidine-4-carboxylic acid amides as anticancer agents.

Lu Y, Wang Z, Li CM, Chen J, Dalton JT, Li W, Miller DD. Lu Y, et al. Bioorg Med Chem. 2010 Jan 15;18(2):477-95. doi: 10.1016/j.bmc.2009.12.020. Epub 2009 Dec 11. Bioorg Med Chem. 2010. PMID: 20056548 Free PMC article.

10

Discovery of 4-substituted methoxybenzoyl-aryl-thiazole as novel anticancer agents: synthesis, biological evaluation, and structure-activity relationships.

Lu Y, Li CM, Wang Z, Ross CR 2nd, Chen J, Dalton JT, Li W, Miller DD. Lu Y, et al. J Med Chem. 2009 Mar 26;52(6):1701-11. doi: 10.1021/jm801449a. J Med Chem. 2009. PMID: 19243174 Free PMC article.

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