O'Brien CA - Search Results

1

Expression levels of gp130 in bone marrow stromal cells determine the magnitude of osteoclastogenic signals generated by IL-6-type cytokines.

O'Brien CA, Lin SC, Bellido T, Manolagas SC. O'Brien CA, et al. J Cell Biochem. 2000 Sep 14;79(4):532-41. doi: 10.1002/1097-4644(20001215)79:4<532::aid-jcb20>3.0.co;2-u. J Cell Biochem. 2000. PMID: 10996844

2

Isolation and characterization of the human gp130 promoter. Regulation by STATS.

O'Brien CA, Manolagas SC. O'Brien CA, et al. J Biol Chem. 1997 Jun 6;272(23):15003-10. doi: 10.1074/jbc.272.23.15003. J Biol Chem. 1997. PMID: 9169475 Free article.

3

Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow.

Lin SC, Yamate T, Taguchi Y, Borba VZ, Girasole G, O'Brien CA, Bellido T, Abe E, Manolagas SC. Lin SC, et al. J Clin Invest. 1997 Oct 15;100(8):1980-90. doi: 10.1172/JCI119729. J Clin Invest. 1997. PMID: 9329961 Free PMC article.

4

Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells.

Bellido T, O'Brien CA, Roberson PK, Manolagas SC. Bellido T, et al. J Biol Chem. 1998 Aug 14;273(33):21137-44. doi: 10.1074/jbc.273.33.21137. J Biol Chem. 1998. PMID: 9694869 Free article.

5

STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130-utilizing cytokines or interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroid hormone.

O'Brien CA, Gubrij I, Lin SC, Saylors RL, Manolagas SC. O'Brien CA, et al. J Biol Chem. 1999 Jul 2;274(27):19301-8. doi: 10.1074/jbc.274.27.19301. J Biol Chem. 1999. PMID: 10383440 Free article.

6

Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin.

Abe E, Yamamoto M, Taguchi Y, Lecka-Czernik B, O'Brien CA, Economides AN, Stahl N, Jilka RL, Manolagas SC. Abe E, et al. J Bone Miner Res. 2000 Apr;15(4):663-73. doi: 10.1359/jbmr.2000.15.4.663. J Bone Miner Res. 2000. PMID: 10780858 Free article.

7

Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity.

Kousteni S, Bellido T, Plotkin LI, O'Brien CA, Bodenner DL, Han L, Han K, DiGregorio GB, Katzenellenbogen JA, Katzenellenbogen BS, Roberson PK, Weinstein RS, Jilka RL, Manolagas SC. Kousteni S, et al. Cell. 2001 Mar 9;104(5):719-30. Cell. 2001. PMID: 11257226 Free article.

8

Cbfa1 does not regulate RANKL gene activity in stromal/osteoblastic cells.

O'Brien CA, Kern B, Gubrij I, Karsenty G, Manolagas SC. O'Brien CA, et al. Bone. 2002 Mar;30(3):453-62. doi: 10.1016/s8756-3282(01)00692-5. Bone. 2002. PMID: 11882458

9

Parathyroid hormone stimulates receptor activator of NFkappa B ligand and inhibits osteoprotegerin expression via protein kinase A activation of cAMP-response element-binding protein.

Fu Q, Jilka RL, Manolagas SC, O'Brien CA. Fu Q, et al. J Biol Chem. 2002 Dec 13;277(50):48868-75. doi: 10.1074/jbc.M208494200. Epub 2002 Oct 2. J Biol Chem. 2002. PMID: 12364326 Free article.

10

Reversal of bone loss in mice by nongenotropic signaling of sex steroids.

Kousteni S, Chen JR, Bellido T, Han L, Ali AA, O'Brien CA, Plotkin L, Fu Q, Mancino AT, Wen Y, Vertino AM, Powers CC, Stewart SA, Ebert R, Parfitt AM, Weinstein RS, Jilka RL, Manolagas SC. Kousteni S, et al. Science. 2002 Oct 25;298(5594):843-6. doi: 10.1126/science.1074935. Science. 2002. PMID: 12399595

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