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A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens.
Mattson NM, Chan AKN, Miyashita K, Mukhaleva E, Chang WH, Yang L, Ma N, Wang Y, Pokharel SP, Li M, Liu Q, Xu X, Chen R, Singh P, Zhang L, Elsayed Z, Chen B, Keen D, Pirrotte P, Rosen ST, Chen J, LaBarge MA, Shively JE, Vaidehi N, Rockne RC, Feng M, Chen CW. Mattson NM, et al. Among authors: vaidehi n. Nat Struct Mol Biol. 2024 Mar;31(3):465-475. doi: 10.1038/s41594-024-01211-y. Epub 2024 Feb 5. Nat Struct Mol Biol. 2024. PMID: 38316881 Free PMC article.
Kinetic steps for alpha-helix formation.
Bertsch RA, Vaidehi N, Chan SI, Goddard WA 3rd. Bertsch RA, et al. Among authors: vaidehi n. Proteins. 1998 Nov 15;33(3):343-57. doi: 10.1002/(sici)1097-0134(19981115)33:3<343::aid-prot4>3.0.co;2-b. Proteins. 1998. PMID: 9829694
Prediction of structure and function of G protein-coupled receptors.
Vaidehi N, Floriano WB, Trabanino R, Hall SE, Freddolino P, Choi EJ, Zamanakos G, Goddard WA 3rd. Vaidehi N, et al. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12622-7. doi: 10.1073/pnas.122357199. Epub 2002 Sep 26. Proc Natl Acad Sci U S A. 2002. PMID: 12351677 Free PMC article.
148 results