Garbay C - Search Results

1

Inhibitors of Ras signal transduction as antitumor agents.

Garbay C, Liu WQ, Vidal M, Roques BP. Garbay C, et al. Biochem Pharmacol. 2000 Oct 15;60(8):1165-9. doi: 10.1016/s0006-2952(00)00428-7. Biochem Pharmacol. 2000. PMID: 11007954 Review.

2

Differential effect of the inhibition of Grb2-SH3 interactions in platelet activation induced by thrombin and by Fc receptor engagement.

Saci A, Liu WQ, Vidal M, Garbay C, Rendu F, Bachelot-Loza C. Saci A, et al. Among authors: garbay c. Biochem J. 2002 May 1;363(Pt 3):717-25. doi: 10.1042/0264-6021:3630717. Biochem J. 2002. PMID: 11964172 Free PMC article.

3

Structure-activity relationships of small phosphopeptides, inhibitors of Grb2 SH2 domain, and their prodrugs.

Liu WQ, Vidal M, Olszowy C, Million E, Lenoir C, Dhôtel H, Garbay C. Liu WQ, et al. Among authors: garbay c. J Med Chem. 2004 Feb 26;47(5):1223-33. doi: 10.1021/jm031005k. J Med Chem. 2004. PMID: 14971902

4

[Design of new anti-tumor agents interrupting deregulated signaling pathways induced by tyrosine kinase proteins. Inhibition of protein-protein interaction involving Grb2].

Vidal M, Liu WQ, Gril B, Assayag F, Poupon MF, Garbay C. Vidal M, et al. Among authors: garbay c. J Soc Biol. 2004;198(2):133-7. J Soc Biol. 2004. PMID: 15368963 Review. French.

5

Grb2-SH3 ligand inhibits the growth of HER2+ cancer cells and has antitumor effects in human cancer xenografts alone and in combination with docetaxel.

Gril B, Vidal M, Assayag F, Poupon MF, Liu WQ, Garbay C. Gril B, et al. Among authors: garbay c. Int J Cancer. 2007 Jul 15;121(2):407-15. doi: 10.1002/ijc.22674. Int J Cancer. 2007. PMID: 17372910 Free PMC article.

6

The cytotoxicity of a Grb2-SH3 inhibitor in Bcr-Abl positive K562 cells.

Ye YB, Lin JY, Chen Q, Liu F, Chen HJ, Li JY, Liu WQ, Garbay C, Vidal M. Ye YB, et al. Among authors: garbay c. Biochem Pharmacol. 2008 Jun 1;75(11):2080-91. doi: 10.1016/j.bcp.2007.12.021. Epub 2008 Mar 22. Biochem Pharmacol. 2008. PMID: 18455151

7

Differential interactions of the growth factor receptor-bound protein 2 N-SH3 domain with son of sevenless and dynamin. Potential role in the Ras-dependent signaling pathway.

Vidal M, Montiel JL, Cussac D, Cornille F, Duchesne M, Parker F, Tocqué B, Roques BP, Garbay C. Vidal M, et al. Among authors: garbay c. J Biol Chem. 1998 Feb 27;273(9):5343-8. doi: 10.1074/jbc.273.9.5343. J Biol Chem. 1998. PMID: 9478994 Free article.

8

A Sos-derived peptidimer blocks the Ras signaling pathway by binding both Grb2 SH3 domains and displays antiproliferative activity.

Cussac D, Vidal M, Leprince C, Liu WQ, Cornille F, Tiraboschi G, Roques BP, Garbay C. Cussac D, et al. Among authors: garbay c. FASEB J. 1999 Jan;13(1):31-8. doi: 10.1096/fasebj.13.1.31. FASEB J. 1999. PMID: 9872927

9

Small peptides containing phosphotyrosine and adjacent alphaMe-phosphotyrosine or its mimetics as highly potent inhibitors of Grb2 SH2 domain.

Liu WQ, Vidal M, Gresh N, Roques BP, Garbay C. Liu WQ, et al. Among authors: garbay c. J Med Chem. 1999 Sep 9;42(18):3737-41. doi: 10.1021/jm9911074. J Med Chem. 1999. PMID: 10479306

10

Inhibition of the ras-dependent mitogenic pathway by phosphopeptide prodrugs with antiproliferative properties.

Liu WQ, Vidal M, Mathé C, Périgaud C, Garbay C. Liu WQ, et al. Among authors: garbay c. Bioorg Med Chem Lett. 2000 Apr 3;10(7):669-72. doi: 10.1016/s0960-894x(00)00077-9. Bioorg Med Chem Lett. 2000. PMID: 10762050

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