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Characterization and effects of methyl-2- (4-aminophenyl)-1, 2-dihydro-1-oxo-7- (2-pyridinylmethoxy)-4-(3,4, 5-trimethoxyphenyl)-3-isoquinoline carboxylate sulfate (T-1032), a novel potent inhibitor of cGMP-binding cGMP-specific phosphodiesterase (PDE5).
Kotera J, Fujishige K, Michibata H, Yuasa K, Kubo A, Nakamura Y, Omori K. Kotera J, et al. Biochem Pharmacol. 2000 Nov 1;60(9):1333-41. doi: 10.1016/s0006-2952(00)00457-3. Biochem Pharmacol. 2000. PMID: 11008127
Expression, structure and chromosomal localization of the human cGMP-binding cGMP-specific phosphodiesterase PDE5A gene.
Yanaka N, Kotera J, Ohtsuka A, Akatsuka H, Imai Y, Michibata H, Fujishige K, Kawai E, Takebayashi S, Okumura K, Omori K. Yanaka N, et al. Among authors: kotera j. Eur J Biochem. 1998 Jul 15;255(2):391-9. doi: 10.1046/j.1432-1327.1998.2550391.x. Eur J Biochem. 1998. PMID: 9716380 Free article.
The deduced amino acid sequence analysis demonstrated that N-terminal amino acid sequence is dissimilar to that of rat PDE5A [Kotera, J., Yanaka, N., Fujishige, K., Imai, Y., Akatsuka, H., Ishizuka, T., Kawashima, K. & Omori, K. (1997) Eur. J. Biochem. 24 …
The deduced amino acid sequence analysis demonstrated that N-terminal amino acid sequence is dissimilar to that of rat PDE5A [Kotera, …
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