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Sequencing of the Francisella tularensis strain Schu 4 genome reveals the shikimate and purine metabolic pathways, targets for the construction of a rationally attenuated auxotrophic vaccine.
Karlsson J, Prior RG, Williams K, Lindler L, Brown KA, Chatwell N, Hjalmarsson K, Loman N, Mack KA, Pallen M, Popek M, Sandström G, Sjöstedt A, Svensson T, Tamas I, Andersson SG, Wren BW, Oyston PC, Titball RW. Karlsson J, et al. Among authors: chatwell n. Microb Comp Genomics. 2000;5(1):25-39. doi: 10.1089/10906590050145249. Microb Comp Genomics. 2000. PMID: 11011763