Loi AG - Search Results

1

Computer-assisted design, synthesis and biological evaluation of novel pyrrolyl heteroaryl sulfones targeted at HIV-1 reverse transcriptase as non-nucleoside inhibitors.

Silvestri R, Artico M, De Martino G, Novellino E, Greco G, Lavecchia A, Massa S, Loi AG, Doratiotto S, La Colla P. Silvestri R, et al. Among authors: loi ag. Bioorg Med Chem. 2000 Sep;8(9):2305-9. doi: 10.1016/s0968-0896(00)00144-9. Bioorg Med Chem. 2000. PMID: 11026542

2

Synthesis, biological evaluation, and binding mode of novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles targeted at the HIV-1 reverse transcriptase.

Silvestri R, Artico M, De Martino G, Ragno R, Massa S, Loddo R, Murgioni C, Loi AG, La Colla P, Pani A. Silvestri R, et al. Among authors: loi ag. J Med Chem. 2002 Apr 11;45(8):1567-76. doi: 10.1021/jm010904a. J Med Chem. 2002. PMID: 11931611

3

Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies.

Silvestri R, De Martino G, La Regina G, Artico M, Massa S, Vargiu L, Mura M, Loi AG, Marceddu T, La Colla P. Silvestri R, et al. Among authors: loi ag. J Med Chem. 2003 Jun 5;46(12):2482-93. doi: 10.1021/jm0211063. J Med Chem. 2003. PMID: 12773052

4

Synthesis and anti-HIV-1 activity of thio analogues of dihydroalkoxybenzyloxopyrimidines.

Mai A, Artico M, Sbardella G, Massa S, Loi AG, Tramontano E, Scano P, La Colla P. Mai A, et al. Among authors: loi ag. J Med Chem. 1995 Aug 18;38(17):3258-63. doi: 10.1021/jm00017a010. J Med Chem. 1995. PMID: 7650679

5

2-Sulfonyl-4-chloroanilino moiety: a potent pharmacophore for the anti-human immunodeficiency virus type 1 activity of pyrrolyl aryl sulfones.

Artico M, Silvestri R, Massa S, Loi AG, Corrias S, Piras G, La Colla P. Artico M, et al. Among authors: loi ag. J Med Chem. 1996 Jan 19;39(2):522-30. doi: 10.1021/jm950568w. J Med Chem. 1996. PMID: 8558522

6

5H-pyrrolo[1,2-b] [1,2,5]benzothiadiazepines (PBTDs): a novel class of non-nucleoside reverse transcriptase inhibitors.

Artico M, Silvestri R, Pagnozzi E, Stefancich G, Massa S, Loi AG, Putzolu M, Corrias S, Spiga MG, La Colla P. Artico M, et al. Among authors: loi ag. Bioorg Med Chem. 1996 Jun;4(6):837-50. doi: 10.1016/0968-0896(96)00075-2. Bioorg Med Chem. 1996. PMID: 8818233

7

Dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: novel non-nucleoside reverse transcriptase inhibitors of the S-DABO series.

Mai A, Artico M, Sbardella G, Quartarone S, Massa S, Loi AG, De Montis A, Scintu F, Putzolu M, La Colla P. Mai A, et al. Among authors: loi ag. J Med Chem. 1997 May 9;40(10):1447-54. doi: 10.1021/jm960802y. J Med Chem. 1997. PMID: 9154967

8

5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4(3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives.

Mai A, Artico M, Sbardella G, Massa S, Novellino E, Greco G, Loi AG, Tramontano E, Marongiu ME, La Colla P. Mai A, et al. Among authors: loi ag. J Med Chem. 1999 Feb 25;42(4):619-27. doi: 10.1021/jm980260f. J Med Chem. 1999. PMID: 10052969

9

Structure-based design, synthesis, and biological evaluation of novel pyrrolyl aryl sulfones: HIV-1 non-nucleoside reverse transcriptase inhibitors active at nanomolar concentrations.

Artico M, Silvestri R, Pagnozzi E, Bruno B, Novellino E, Greco G, Massa S, Ettorre A, Loi AG, Scintu F, La Colla P. Artico M, et al. Among authors: loi ag. J Med Chem. 2000 May 4;43(9):1886-91. doi: 10.1021/jm9901125. J Med Chem. 2000. PMID: 10794705

10

Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of isoddA and their phosphates as prodrugs.

Franchetti P, Cappellacci L, Grifantini M, Messini L, abu Sheikha G, Loi AG, Tramontano E, de Montis A, Spiga MG, La Colla P. Franchetti P, et al. Among authors: loi ag. J Med Chem. 1994 Oct 14;37(21):3534-41. doi: 10.1021/jm00047a011. J Med Chem. 1994. PMID: 7523675

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