Lybrand TP - Search Results

1

Refinement of the structure of the ligand-occupied cholecystokinin receptor using a photolabile amino-terminal probe.

Ding XQ, Dolu V, Hadac EM, Holicky EL, Pinon DI, Lybrand TP, Miller LJ. Ding XQ, et al. Among authors: lybrand tp. J Biol Chem. 2001 Feb 9;276(6):4236-44. doi: 10.1074/jbc.M003798200. Epub 2000 Oct 24. J Biol Chem. 2001. PMID: 11050076 Free article.

2

Refinement of the conformation of a critical region of charge-charge interaction between cholecystokinin and its receptor.

Ding XQ, Pinon DI, Furse KE, Lybrand TP, Miller LJ. Ding XQ, et al. Among authors: lybrand tp. Mol Pharmacol. 2002 May;61(5):1041-52. doi: 10.1124/mol.61.5.1041. Mol Pharmacol. 2002. PMID: 11961122

3

Interaction among four residues distributed through the secretin pharmacophore and a focused region of the secretin receptor amino terminus.

Dong M, Zang M, Pinon DI, Li Z, Lybrand TP, Miller LJ. Dong M, et al. Among authors: lybrand tp. Mol Endocrinol. 2002 Nov;16(11):2490-501. doi: 10.1210/me.2002-0111. Mol Endocrinol. 2002. PMID: 12403838

4

Molecular basis of agonist binding to the type A cholecystokinin receptor.

Miller LJ, Lybrand TP. Miller LJ, et al. Among authors: lybrand tp. Pharmacol Toxicol. 2002 Dec;91(6):282-5. doi: 10.1034/j.1600-0773.2002.910603.x. Pharmacol Toxicol. 2002. PMID: 12688369 Review.

5

Spatial approximation between a photolabile residue in position 13 of secretin and the amino terminus of the secretin receptor.

Zang M, Dong M, Pinon DI, Ding XQ, Hadac EM, Li Z, Lybrand TP, Miller LJ. Zang M, et al. Among authors: lybrand tp. Mol Pharmacol. 2003 May;63(5):993-1001. doi: 10.1124/mol.63.5.993. Mol Pharmacol. 2003. PMID: 12695527

6

Spatial approximation between two residues in the mid-region of secretin and the amino terminus of its receptor. Incorporation of seven sets of such constraints into a three-dimensional model of the agonist-bound secretin receptor.

Dong M, Li Z, Zang M, Pinon DI, Lybrand TP, Miller LJ. Dong M, et al. Among authors: lybrand tp. J Biol Chem. 2003 Nov 28;278(48):48300-12. doi: 10.1074/jbc.M309166200. Epub 2003 Sep 18. J Biol Chem. 2003. PMID: 14500709 Free article.

7

Spatial approximation between the amino terminus of a peptide agonist and the top of the sixth transmembrane segment of the secretin receptor.

Dong M, Li Z, Pinon DI, Lybrand TP, Miller LJ. Dong M, et al. Among authors: lybrand tp. J Biol Chem. 2004 Jan 23;279(4):2894-903. doi: 10.1074/jbc.M310407200. Epub 2003 Oct 30. J Biol Chem. 2004. PMID: 14593094 Free article.

8

Measurement of intermolecular distances for the natural agonist Peptide docked at the cholecystokinin receptor expressed in situ using fluorescence resonance energy transfer.

Harikumar KG, Pinon DI, Wessels WS, Dawson ES, Lybrand TP, Prendergast FG, Miller LJ. Harikumar KG, et al. Among authors: lybrand tp. Mol Pharmacol. 2004 Jan;65(1):28-35. doi: 10.1124/mol.65.1.28. Mol Pharmacol. 2004. PMID: 14722234

9

Novel benzodiazepine photoaffinity probe stereoselectively labels a site deep within the membrane-spanning domain of the cholecystokinin receptor.

Hadac EM, Dawson ES, Darrow JW, Sugg EE, Lybrand TP, Miller LJ. Hadac EM, et al. Among authors: lybrand tp. J Med Chem. 2006 Feb 9;49(3):850-63. doi: 10.1021/jm049072h. J Med Chem. 2006. PMID: 16451051 Free PMC article.

10

A peptide agonist acts by occupation of a monomeric G protein-coupled receptor: dual sites of covalent attachment to domains near TM1 and TM7 of the same molecule make biologically significant domain-swapped dimerization unlikely.

Hadac EM, Ji Z, Pinon DI, Henne RM, Lybrand TP, Miller LJ. Hadac EM, et al. Among authors: lybrand tp. J Med Chem. 1999 Jun 17;42(12):2105-11. doi: 10.1021/jm980732q. J Med Chem. 1999. PMID: 10377216

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