Zhang J - Search Results

1

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism.

Wei P, Zhang J, Egan-Hafley M, Liang S, Moore DD. Wei P, et al. Among authors: zhang j. Nature. 2000 Oct 19;407(6806):920-3. doi: 10.1038/35038112. Nature. 2000. PMID: 11057673

2

Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR.

Zhang J, Huang W, Chua SS, Wei P, Moore DD. Zhang J, et al. Science. 2002 Oct 11;298(5592):422-4. doi: 10.1126/science.1073502. Science. 2002. PMID: 12376703

3

Role of the constitutive androstane receptor in xenobiotic-induced thyroid hormone metabolism.

Qatanani M, Zhang J, Moore DD. Qatanani M, et al. Among authors: zhang j. Endocrinology. 2005 Mar;146(3):995-1002. doi: 10.1210/en.2004-1350. Epub 2004 Nov 24. Endocrinology. 2005. PMID: 15564320

4

Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.

Wei P, Zhang J, Dowhan DH, Han Y, Moore DD. Wei P, et al. Among authors: zhang j. Pharmacogenomics J. 2002;2(2):117-26. doi: 10.1038/sj.tpj.6500087. Pharmacogenomics J. 2002. PMID: 12049174

5

Induction of bilirubin clearance by the constitutive androstane receptor (CAR).

Huang W, Zhang J, Chua SS, Qatanani M, Han Y, Granata R, Moore DD. Huang W, et al. Among authors: zhang j. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4156-61. doi: 10.1073/pnas.0630614100. Epub 2003 Mar 18. Proc Natl Acad Sci U S A. 2003. PMID: 12644704 Free PMC article.

6

A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR.

Huang W, Zhang J, Moore DD. Huang W, et al. Among authors: zhang j. J Clin Invest. 2004 Jan;113(1):137-43. doi: 10.1172/JCI18385. J Clin Invest. 2004. PMID: 14702117 Free PMC article.

7

Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR.

Huang W, Zhang J, Wei P, Schrader WT, Moore DD. Huang W, et al. Among authors: zhang j. Mol Endocrinol. 2004 Oct;18(10):2402-8. doi: 10.1210/me.2004-0046. Epub 2004 Jul 22. Mol Endocrinol. 2004. PMID: 15272053

8

The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.

Zhang J, Huang W, Qatanani M, Evans RM, Moore DD. Zhang J, et al. J Biol Chem. 2004 Nov 19;279(47):49517-22. doi: 10.1074/jbc.M409041200. Epub 2004 Sep 8. J Biol Chem. 2004. PMID: 15358766 Free article.

9

Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor.

Huang W, Zhang J, Washington M, Liu J, Parant JM, Lozano G, Moore DD. Huang W, et al. Among authors: zhang j. Mol Endocrinol. 2005 Jun;19(6):1646-53. doi: 10.1210/me.2004-0520. Epub 2005 Apr 14. Mol Endocrinol. 2005. PMID: 15831521

10

CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.

Anakk S, Kalsotra A, Kikuta Y, Huang W, Zhang J, Staudinger JL, Moore DD, Strobel HW. Anakk S, et al. Among authors: zhang j. Pharmacogenomics J. 2004;4(2):91-101. doi: 10.1038/sj.tpj.6500222. Pharmacogenomics J. 2004. PMID: 14770174

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