Chi L - Search Results

1

Rational design, synthesis, and biological activity of benzoxazinones as novel factor Xa inhibitors.

Dudley DA, Bunker AM, Chi L, Cody WL, Holland DR, Ignasiak DP, Janiczek-Dolphin N, McClanahan TB, Mertz TE, Narasimhan LS, Rapundalo ST, Trautschold JA, Van Huis CA, Edmunds JJ. Dudley DA, et al. Among authors: chi l. J Med Chem. 2000 Nov 2;43(22):4063-70. doi: 10.1021/jm000074l. J Med Chem. 2000. PMID: 11063603

2

Design, synthesis, and biological activity of potent and selective inhibitors of blood coagulation factor Xa.

Willardsen JA, Dudley DA, Cody WL, Chi L, McClanahan TB, Mertz TE, Potoczak RE, Narasimhan LS, Holland DR, Rapundalo ST, Edmunds JJ. Willardsen JA, et al. Among authors: chi l. J Med Chem. 2004 Jul 29;47(16):4089-99. doi: 10.1021/jm0497491. J Med Chem. 2004. PMID: 15267248

3

In vitro and in vivo antithrombotic activity of PD-198961, a novel synthetic factor Xa inhibitor.

Chi L, Peng YW, Gibson G, Hicks G, Mertz TE, Rapundalo S, Janiczek N, Edmunds JJ, Leadley R. Chi L, et al. J Cardiovasc Pharmacol. 2004 Oct;44(4):493-500. doi: 10.1097/01.fjc.0000141475.14007.ab. J Cardiovasc Pharmacol. 2004. PMID: 15454859

4

Assessment of ex vivo pharmacodynamic markers during inhibition of thrombosis by CI-1031 (ZK-807834), a novel direct factor Xa inhibitor.

Chi L, Pen YW, Potoczak R, Gibson G, Hicks G, Mertz TE, Janiczek N, Juneau PL, Gallagher K, Leadley R. Chi L, et al. Pharmacology. 2002 Feb;64(2):76-83. doi: 10.1159/000056154. Pharmacology. 2002. PMID: 11803247

5

The discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide (PD 0348292), an orally efficacious factor Xa inhibitor.

Kohrt JT, Bigge CF, Bryant JW, Casimiro-Garcia A, Chi L, Cody WL, Dahring T, Dudley DA, Filipski KJ, Haarer S, Heemstra R, Janiczek N, Narasimhan L, McClanahan T, Peterson JT, Sahasrabudhe V, Schaum R, Van Huis CA, Welch KM, Zhang E, Leadley RJ, Edmunds JJ. Kohrt JT, et al. Among authors: chi l. Chem Biol Drug Des. 2007 Aug;70(2):100-12. doi: 10.1111/j.1747-0285.2007.00539.x. Chem Biol Drug Des. 2007. PMID: 17683371

6

Effects of a factor Xa inhibitor, DX-9065a, in a novel rabbit model of venous thrombosis.

Rogers KL, Chi L, Rapundalo ST, Kramer JB, Gallagher KP. Rogers KL, et al. Among authors: chi l. Basic Res Cardiol. 1999 Feb;94(1):15-22. doi: 10.1007/s003950050122. Basic Res Cardiol. 1999. PMID: 10097826

7

Inhibitors of blood coagulation factors Xa and IIa synergize to reduce thrombus weight and thrombin generation in vivo and in vitro.

Gould WR, McClanahan TB, Welch KM, Baxi SM, Saiya-Cork K, Chi L, Johnson TR, Leadley RJ. Gould WR, et al. Among authors: chi l. J Thromb Haemost. 2006 Apr;4(4):834-41. doi: 10.1111/j.1538-7836.2006.01830.x. J Thromb Haemost. 2006. PMID: 16634754 Free article.

8

P2Y1 receptor antagonists as novel antithrombotic agents.

Pfefferkorn JA, Choi C, Winters T, Kennedy R, Chi L, Perrin LA, Lu G, Ping YW, McClanahan T, Schroeder R, Leininger MT, Geyer A, Schefzick S, Atherton J. Pfefferkorn JA, et al. Among authors: chi l. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3338-43. doi: 10.1016/j.bmcl.2008.04.028. Epub 2008 Apr 15. Bioorg Med Chem Lett. 2008. PMID: 18445527

9

A novel model of venous thrombosis in the vena cava of rabbits.

Chi L, Saganek LJ, Rogers KL, Mertz TE, Metz AL, Uprichard AC, Gallagher KP. Chi L, et al. J Pharmacol Toxicol Methods. 1998 Jun;39(4):193-202. doi: 10.1016/s1056-8719(98)00024-0. J Pharmacol Toxicol Methods. 1998. PMID: 9845298

10

Antithrombotic effect of LB-30057 (CI-1028), a new synthetic thrombin inhibitor, in a rabbit model of thrombosis: comparison with inogatran.

Chi L, Mertz TE, Rogers KL, Janiczek N, Peng YW, Saganek L, Bousley RF, Juneau PL, Uprichard AC, Gallagher KP. Chi L, et al. J Thromb Thrombolysis. 2001 Feb;11(1):19-31. doi: 10.1023/a:1008900109285. J Thromb Thrombolysis. 2001. PMID: 11248787

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,348 results

Search Page

Filters