Braun MP - Search Results

1

High-throughput simultaneous determination of the HIV protease inhibitors indinavir and L-756423 in human plasma using semi-automated 96-well solid phase extraction and LC-MS/MS.

Rose MJ, Merschman SA, Eisenhandler R, Woolf EJ, Yeh KC, Lin L, Fang W, Hsieh J, Braun MP, Gatto GJ, Matuszewski BK. Rose MJ, et al. Among authors: braun mp. J Pharm Biomed Anal. 2000 Dec 15;24(2):291-305. doi: 10.1016/s0731-7085(00)00420-9. J Pharm Biomed Anal. 2000. PMID: 11130208

2

LC/MS/MS plasma assay for the peptidomimetic VLA4 antagonist I and its major active metabolite II: for treatment of asthma by inhalation.

Fisher AL, DePuy E, Jayaraj A, Raab C, Braun M, Ellis-Hutchings M, Zhang J, Rogers JD, Musson DG. Fisher AL, et al. J Pharm Biomed Anal. 2002 Jan 1;27(1-2):57-71. doi: 10.1016/s0731-7085(01)00496-4. J Pharm Biomed Anal. 2002. PMID: 11682211

3

Simultaneous determination of a novel KDR kinase inhibitor and its N-oxide metabolite in human plasma using 96-well solid-phase extraction and liquid chromatography/tandem mass spectrometry.

Xu Y, Du L, Soli ED, Braun MP, Dean DC, Musson DG. Xu Y, et al. Among authors: braun mp. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Mar 25;817(2):287-96. doi: 10.1016/j.jchromb.2004.12.019. J Chromatogr B Analyt Technol Biomed Life Sci. 2005. PMID: 15686997

4

Mechanistic studies on the reversible metabolism of rofecoxib to 5-hydroxyrofecoxib in the rat: evidence for transient ring opening of a substituted 2-furanone derivative using stable isotope-labeling techniques.

Baillie TA, Halpin RA, Matuszewski BK, Geer LA, Chavez-Eng CM, Dean D, Braun M, Doss G, Jones A, Marks T, Melillo D, Vyas KP. Baillie TA, et al. Drug Metab Dispos. 2001 Dec;29(12):1614-28. Drug Metab Dispos. 2001. PMID: 11717181

5

Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humans.

Poon GK, Chen Q, Teffera Y, Ngui JS, Griffin PR, Braun MP, Doss GA, Freeden C, Stearns RA, Evans DC, Baillie TA, Tang W. Poon GK, et al. Among authors: braun mp. Drug Metab Dispos. 2001 Dec;29(12):1608-13. Drug Metab Dispos. 2001. PMID: 11717180

6

Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites.

Tang W, Stearns RA, Bandiera SM, Zhang Y, Raab C, Braun MP, Dean DC, Pang J, Leung KH, Doss GA, Strauss JR, Kwei GY, Rushmore TH, Chiu SH, Baillie TA. Tang W, et al. Among authors: braun mp. Drug Metab Dispos. 1999 Mar;27(3):365-72. Drug Metab Dispos. 1999. PMID: 10064567

7

Metabolism and renal elimination of gaboxadol in humans: role of UDP-glucuronosyltransferases and transporters.

Chu XY, Liang Y, Cai X, Cuevas-Licea K, Rippley RK, Kassahun K, Shou M, Braun MP, Doss GA, Anari MR, Evers R. Chu XY, et al. Among authors: braun mp. Pharm Res. 2009 Feb;26(2):459-68. doi: 10.1007/s11095-008-9799-5. Epub 2008 Dec 11. Pharm Res. 2009. PMID: 19082692

8

Characterization of rat and human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of diclofenac.

King C, Tang W, Ngui J, Tephly T, Braun M. King C, et al. Toxicol Sci. 2001 May;61(1):49-53. doi: 10.1093/toxsci/61.1.49. Toxicol Sci. 2001. PMID: 11294973

9

Metabolism of MK-0524, a prostaglandin D2 receptor 1 antagonist, in microsomes and hepatocytes from preclinical species and humans.

Dean BJ, Chang S, Silva Elipe MV, Xia YQ, Braun M, Soli E, Zhao Y, Franklin RB, Karanam B. Dean BJ, et al. Drug Metab Dispos. 2007 Feb;35(2):283-92. doi: 10.1124/dmd.106.011551. Epub 2006 Nov 28. Drug Metab Dispos. 2007. PMID: 17132765

10

A potent and orally active HIV-1 integrase inhibitor.

Egbertson MS, Moritz HM, Melamed JY, Han W, Perlow DS, Kuo MS, Embrey M, Vacca JP, Zrada MM, Cortes AR, Wallace A, Leonard Y, Hazuda DJ, Miller MD, Felock PJ, Stillmock KA, Witmer MV, Schleif W, Gabryelski LJ, Moyer G, Ellis JD, Jin L, Xu W, Braun MP, Kassahun K, Tsou NN, Young SD. Egbertson MS, et al. Among authors: braun mp. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1392-8. doi: 10.1016/j.bmcl.2006.11.080. Epub 2006 Dec 3. Bioorg Med Chem Lett. 2007. PMID: 17194584

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