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971 results

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Page 1
PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance.
Kubota N, Terauchi Y, Miki H, Tamemoto H, Yamauchi T, Komeda K, Satoh S, Nakano R, Ishii C, Sugiyama T, Eto K, Tsubamoto Y, Okuno A, Murakami K, Sekihara H, Hasegawa G, Naito M, Toyoshima Y, Tanaka S, Shiota K, Kitamura T, Fujita T, Ezaki O, Aizawa S, Kadowaki T, et al. Kubota N, et al. Among authors: miki h. Mol Cell. 1999 Oct;4(4):597-609. doi: 10.1016/s1097-2765(00)80210-5. Mol Cell. 1999. PMID: 10549291 Free article.
The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance.
Yamauchi T, Kamon J, Waki H, Murakami K, Motojima K, Komeda K, Ide T, Kubota N, Terauchi Y, Tobe K, Miki H, Tsuchida A, Akanuma Y, Nagai R, Kimura S, Kadowaki T. Yamauchi T, et al. Among authors: miki h. J Biol Chem. 2001 Nov 2;276(44):41245-54. doi: 10.1074/jbc.M103241200. Epub 2001 Aug 31. J Biol Chem. 2001. PMID: 11533050 Free article.
The role of PPARgamma as a thrifty gene both in mice and humans.
Hara K, Kubota N, Tobe K, Terauchi Y, Miki H, Komeda K, Tamemoto H, Yamauchi T, Hagura R, Ito C, Akanuma Y, Kadowaki T. Hara K, et al. Among authors: miki h. Br J Nutr. 2000 Dec;84 Suppl 2:S235-9. doi: 10.1079/096582197388608. Br J Nutr. 2000. PMID: 11242476
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes.
Yamauchi T, Waki H, Kamon J, Murakami K, Motojima K, Komeda K, Miki H, Kubota N, Terauchi Y, Tsuchida A, Tsuboyama-Kasaoka N, Yamauchi N, Ide T, Hori W, Kato S, Fukayama M, Akanuma Y, Ezaki O, Itai A, Nagai R, Kimura S, Tobe K, Kagechika H, Shudo K, Kadowaki T. Yamauchi T, et al. Among authors: miki h. J Clin Invest. 2001 Oct;108(7):1001-13. doi: 10.1172/JCI12864. J Clin Invest. 2001. PMID: 11581301 Free PMC article.
Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.
Kubota N, Tobe K, Terauchi Y, Eto K, Yamauchi T, Suzuki R, Tsubamoto Y, Komeda K, Nakano R, Miki H, Satoh S, Sekihara H, Sciacchitano S, Lesniak M, Aizawa S, Nagai R, Kimura S, Akanuma Y, Taylor SI, Kadowaki T. Kubota N, et al. Among authors: miki h. Diabetes. 2000 Nov;49(11):1880-9. doi: 10.2337/diabetes.49.11.1880. Diabetes. 2000. PMID: 11078455
Combinations of olmesartan and a calcium channel blocker or a diuretic in elderly hypertensive patients: a randomized, controlled trial.
Ogihara T, Saruta T, Rakugi H, Saito I, Shimamoto K, Matsuoka H, Shimada K, Ito S, Horiuchi M, Imaizumi T, Takishita S, Higaki J, Katayama S, Kimura G, Umemura S, Ura N, Hayashi K, Odawara M, Tanahashi N, Ishimitsu T, Kashihara N, Morita S, Teramukai S; COLM Investigators. Ogihara T, et al. J Hypertens. 2014 Oct;32(10):2054-63; discussiom 2063. doi: 10.1097/HJH.0000000000000281. J Hypertens. 2014. PMID: 24999799 Free PMC article. Clinical Trial.
971 results