Petros AM - Search Results

1

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies.

Petros AM, Nettesheim DG, Wang Y, Olejniczak ET, Meadows RP, Mack J, Swift K, Matayoshi ED, Zhang H, Thompson CB, Fesik SW. Petros AM, et al. Protein Sci. 2000 Dec;9(12):2528-34. doi: 10.1110/ps.9.12.2528. Protein Sci. 2000. PMID: 11206074 Free PMC article.

2

Solution structure of a Bcl-2 homolog from Kaposi sarcoma virus.

Huang Q, Petros AM, Virgin HW, Fesik SW, Olejniczak ET. Huang Q, et al. Among authors: petros am. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3428-33. doi: 10.1073/pnas.062525799. Proc Natl Acad Sci U S A. 2002. PMID: 11904405 Free PMC article.

3

Solution structure of the BHRF1 protein from Epstein-Barr virus, a homolog of human Bcl-2.

Huang Q, Petros AM, Virgin HW, Fesik SW, Olejniczak ET. Huang Q, et al. Among authors: petros am. J Mol Biol. 2003 Oct 3;332(5):1123-30. doi: 10.1016/j.jmb.2003.08.007. J Mol Biol. 2003. PMID: 14499614

4

Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.

Petros AM, Gunasekera A, Xu N, Olejniczak ET, Fesik SW. Petros AM, et al. FEBS Lett. 2004 Feb 13;559(1-3):171-4. doi: 10.1016/S0014-5793(04)00059-6. FEBS Lett. 2004. PMID: 14960327 Free article.

5

Structural biology of the Bcl-2 family of proteins.

Petros AM, Olejniczak ET, Fesik SW. Petros AM, et al. Biochim Biophys Acta. 2004 Mar 1;1644(2-3):83-94. doi: 10.1016/j.bbamcr.2003.08.012. Biochim Biophys Acta. 2004. PMID: 14996493 Free article. Review.

6

Discovery of a potent inhibitor of the antiapoptotic protein Bcl-xL from NMR and parallel synthesis.

Petros AM, Dinges J, Augeri DJ, Baumeister SA, Betebenner DA, Bures MG, Elmore SW, Hajduk PJ, Joseph MK, Landis SK, Nettesheim DG, Rosenberg SH, Shen W, Thomas S, Wang X, Zanze I, Zhang H, Fesik SW. Petros AM, et al. J Med Chem. 2006 Jan 26;49(2):656-63. doi: 10.1021/jm0507532. J Med Chem. 2006. PMID: 16420051

7

Three-dimensional structure of the FK506 binding protein/ascomycin complex in solution by heteronuclear three- and four-dimensional NMR.

Meadows RP, Nettesheim DG, Xu RX, Olejniczak ET, Petros AM, Holzman TF, Severin J, Gubbins E, Smith H, Fesik SW. Meadows RP, et al. Among authors: petros am. Biochemistry. 1993 Jan 26;32(3):754-65. doi: 10.1021/bi00054a004. Biochemistry. 1993. PMID: 7678499

8

Solution structure of the antiapoptotic protein bcl-2.

Petros AM, Medek A, Nettesheim DG, Kim DH, Yoon HS, Swift K, Matayoshi ED, Oltersdorf T, Fesik SW. Petros AM, et al. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3012-7. doi: 10.1073/pnas.041619798. Epub 2001 Feb 27. Proc Natl Acad Sci U S A. 2001. PMID: 11248023 Free PMC article.

9

Structure of the N-terminal RNA-binding domain of the SARS CoV nucleocapsid protein.

Huang Q, Yu L, Petros AM, Gunasekera A, Liu Z, Xu N, Hajduk P, Mack J, Fesik SW, Olejniczak ET. Huang Q, et al. Among authors: petros am. Biochemistry. 2004 May 25;43(20):6059-63. doi: 10.1021/bi036155b. Biochemistry. 2004. PMID: 15147189

10

Design, synthesis, and computational studies of inhibitors of Bcl-XL.

Park CM, Oie T, Petros AM, Zhang H, Nimmer PM, Henry RF, Elmore SW. Park CM, et al. Among authors: petros am. J Am Chem Soc. 2006 Dec 20;128(50):16206-12. doi: 10.1021/ja0650347. J Am Chem Soc. 2006. PMID: 17165773

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