Houba PH - Search Results

1

A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer.

Houba PH, Boven E, van der Meulen-Muileman IH, Leenders RG, Scheeren JW, Pinedo HM, Haisma HJ. Houba PH, et al. Br J Cancer. 2001 Feb;84(4):550-7. doi: 10.1054/bjoc.2000.1640. Br J Cancer. 2001. PMID: 11207053 Free PMC article.

2

Characterization of novel anthracycline prodrugs activated by human beta-glucuronidase for use in antibody-directed enzyme prodrug therapy.

Houba PH, Leenders RG, Boven E, Scheeren JW, Pinedo HM, Haisma HJ. Houba PH, et al. Biochem Pharmacol. 1996 Aug 9;52(3):455-63. doi: 10.1016/0006-2952(96)00248-1. Biochem Pharmacol. 1996. PMID: 8687500

3

Improved characteristics of a human beta-glucuronidase-antibody conjugate after deglycosylation for use in antibody-directed enzyme prodrug therapy.

Houba PH, Boven E, Haisma HJ. Houba PH, et al. Bioconjug Chem. 1996 Sep-Oct;7(5):606-11. doi: 10.1021/bc960055j. Bioconjug Chem. 1996. PMID: 8889024

4

The efficacy of the anthracycline prodrug daunorubicin-GA3 in human ovarian cancer xenografts.

Houba PH, Boven E, Erkelens CA, Leenders RG, Scheeren JW, Pinedo HM, Haisma HJ. Houba PH, et al. Br J Cancer. 1998 Dec;78(12):1600-6. doi: 10.1038/bjc.1998.729. Br J Cancer. 1998. PMID: 9862570 Free PMC article.

5

Distribution and pharmacokinetics of the prodrug daunorubicin-GA3 in nude mice bearing human ovarian cancer xenografts.

Houba PH, Boven E, van der Meulen-Muileman IH, Leenders RG, Scheeren JW, Pinedo HM, Haisma HJ. Houba PH, et al. Biochem Pharmacol. 1999 Mar 15;57(6):673-80. doi: 10.1016/s0006-2952(98)00343-8. Biochem Pharmacol. 1999. PMID: 10037453

6

Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody beta-glucuronidase conjugate.

Houba PH, Boven E, van der Meulen-Muileman IH, Leenders RG, Scheeren JW, Pinedo HM, Haisma HJ. Houba PH, et al. Int J Cancer. 2001 Feb 15;91(4):550-4. doi: 10.1002/1097-0215(200002)9999:9999<::aid-ijc1075>3.0.co;2-l. Int J Cancer. 2001. PMID: 11251980

7

Novel anthracycline-spacer-beta-glucuronide,-beta-glucoside, and -beta-galactoside prodrugs for application in selective chemotherapy.

Leenders RG, Damen EW, Bijsterveld EJ, Scheeren HW, Houba PH, van der Meulen-Muileman IH, Boven E, Haisma HJ. Leenders RG, et al. Among authors: houba ph. Bioorg Med Chem. 1999 Aug;7(8):1597-610. doi: 10.1016/s0968-0896(99)00095-4. Bioorg Med Chem. 1999. PMID: 10482452

8

Overproduction of prismane protein in Desulfovibrio vulgaris (Hildenborough): evidence for a second S = 1/2-spin system in the one-electron reduced state.

Stokkermans JP, Houba PH, Pierik AJ, Hagen WR, van Dongen WM, Veeger C. Stokkermans JP, et al. Among authors: houba ph. Eur J Biochem. 1992 Dec 15;210(3):983-8. doi: 10.1111/j.1432-1033.1992.tb17503.x. Eur J Biochem. 1992. PMID: 1336462 Free article.

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